RecruitingACTRN12614000097640

Exercise preference in overweight adults with clinical depression: a pilot study

A randomised controlled trial investigating the suitability of three formats of exercise intervention for overweight or obese adults with clinical depression.


Sponsor

Nick Buckley

Enrollment

35 participants

Start Date

May 1, 2014

Study Type

Interventional

Conditions

Summary

The propsed study will investigate the suitablity (particularly enjoyment, motivation to continue) of three formats of exercise intervention (Moderate Intensity Personal Preference; Moderate Intensity Steady State; and High Intensity Interval Training) for overweight or obese individuals with clinical depression. In essence, the proposed research will act as a feasibility/pilot study for a later study, which will be based on the results of the proposed research. In this future study a 12 week exercise program will be implemented (based on the proposed study outcomes) which will be compared to and used alongside a “gold standard” treatment of Cognitive Behaviour Therapy for depression. It is important to understand exercise preferences and motivation to continue exercise in this population prior to designing this treatment protocol. We expect that the format of exercise (high intensity vs moderate intensity; interval vs steady state vs personal preference) will differentially affect motivation and enjoyment as well as markers of inflammation, appetite, symptoms of depression and sleep quality.


Eligibility

Sex: Both males and femalesMin Age: 17 YearssMax Age: 45 Yearss

Plain Language Summary

Simplified for easier understanding

This pilot study is looking at which type of exercise format — moderate intensity at personal preference, moderate intensity at a steady pace, or high intensity interval training — is most enjoyable and motivating for overweight or obese adults who also have depression. The study will also look at how each exercise type affects inflammation, appetite, mood, and sleep. This information will be used to design a larger, full exercise trial for depression. You may be eligible if: - You are between 17 and 45 years of age (or 18-45 if not a tertiary student) - You have been diagnosed with depression (DSM-IV-TR criteria) - You have a BMI over 25 (overweight or obese) - You are not currently attending therapy and agree not to start new therapy during the study - If you take antidepressants, you have been on a stable dose for at least 3 weeks - If female, you are not pregnant or trying to become pregnant - You understand written and spoken English You may NOT be eligible if: - You have a diagnosis of psychosis, personality disorder, or another mood disorder - You have had a heart attack or stroke, or have active heart disease - You have a serious or unstable medical condition (other than obesity) - You have a substance dependency requiring treatment - You have had suicidal thoughts in the past or made a recent attempt - You have type 1 or insulin-dependent type 2 diabetes Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

All exercise interventions will be conducted 3x per week over 6 weeks, with approximately 45-60mins of exercise per session, including warm up and cool down. All exercise is supervised and conducted i

All exercise interventions will be conducted 3x per week over 6 weeks, with approximately 45-60mins of exercise per session, including warm up and cool down. All exercise is supervised and conducted in individual format. Intensity is calculated via an initial VO2max test. Arm 1 - Moderate Intensity Steady State Exercise - Participant performs steady state stationary cycling at a moderate intensity (60-65% VO2peak). Arm 2 - High Intensity Interval Training - Participant performs repeated short bouts of high intensity exercise (e.g. 1min @ 95-100% VO2peak) followed by lower intensity recovery exercise (e.g. 4mins @ 40-45% VO2peak) on a stationary cycle.


Locations(1)

WA, Australia

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