RecruitingACTRN12614000097640

Exercise preference in overweight adults with clinical depression: a pilot study

A randomised controlled trial investigating the suitability of three formats of exercise intervention for overweight or obese adults with clinical depression.

Sponsor

Nick Buckley

Enrollment

35 participants

Start Date

May 1, 2014

Study Type

Interventional

Conditions

Overweight/Obesity Clinical Depression

Summary

The propsed study will investigate the suitablity (particularly enjoyment, motivation to continue) of three formats of exercise intervention (Moderate Intensity Personal Preference; Moderate Intensity Steady State; and High Intensity Interval Training) for overweight or obese individuals with clinical depression. In essence, the proposed research will act as a feasibility/pilot study for a later study, which will be based on the results of the proposed research. In this future study a 12 week exercise program will be implemented (based on the proposed study outcomes) which will be compared to and used alongside a “gold standard” treatment of Cognitive Behaviour Therapy for depression. It is important to understand exercise preferences and motivation to continue exercise in this population prior to designing this treatment protocol. We expect that the format of exercise (high intensity vs moderate intensity; interval vs steady state vs personal preference) will differentially affect motivation and enjoyment as well as markers of inflammation, appetite, symptoms of depression and sleep quality.

Eligibility

Sex: Both males and femalesMin Age: 17 YearssMax Age: 45 Yearss

Inclusion Criteria9

DSM-IV-TR Diagnosis of depression
Overweight or Obese (BMI: >25)
Not have diagnosed diabetes
Willing and able to participate in exercise intervention
Older than 18 years of age, younger than 45 years of age (if attending an Australian Tertiary Institution, older than 17 years of age)
Stable use of antidepressents (at least 3 weeks on regular dose)
No current engagement in therapy and willingness to postpone new therapy for the duration of participation
If female, must not be pregnant or attempting to become pregnant.
Understand written and spoken English (a conversational level of english is all that is required)

Exclusion Criteria6

Certain Mental disorders (Psychosis, Personality Disorder or other Mood Disorders - either ICD-10 or DSM-IV-TR)
Previous cardiovascular incident (e.g. heart attack, stroke)
Current cardiovascular disease (i.e. CHD)
Serious or unstable medical conditions (other than obesity)
Substance dependence requiring rehabilitation/detoxification
Current suicidal ideation or recent attempt (previous 24months)

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

All exercise interventions will be conducted 3x per week over 6 weeks, with approximately 45-60mins of exercise per session, including warm up and cool down. All exercise is supervised and conducted in individual format. Intensity is calculated via an initial VO2max test. Arm 1 - Moderate Intensity Steady State Exercise - Participant performs steady state stationary cycling at a moderate intensity (60-65% VO2peak). Arm 2 - High Intensity Interval Training - Participant performs repeated short bouts of high intensity exercise (e.g. 1min @ 95-100% VO2peak) followed by lower intensity recovery exercise (e.g. 4mins @ 40-45% VO2peak) on a stationary cycle.