Overweight/Obesity Clinical Trials

21 recruitingLast updated: July 16, 2026

There are 21 actively recruiting overweight/obesity clinical trials across 10 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 4. Top locations include Chengdu, Sichuan, China, Shanghai, Shanghai Municipality, China, Aurora, Colorado, United States. Updated daily from ClinicalTrials.gov.


Overweight/Obesity Trials at a Glance

21 actively recruiting trials for overweight/obesity are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 12 trials, with the heaviest enrollment activity in Chengdu, Shanghai, and Aurora. Lead sponsors running overweight/obesity studies include Beijing QL Biopharmaceutical Co.,Ltd, Shanghai Zhongshan Hospital, and University of Colorado, Denver.

Browse overweight/obesity trials by phase

Treatments under study

About Overweight/Obesity Clinical Trials

Looking for clinical trials for Overweight/Obesity? There are currently 36 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Overweight/Obesity trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Overweight/Obesity clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 21 trials

Recruiting
Not Applicable

Efficacy and Safety of Akkermansia Muciniphila AKM Lab-01 for Overweight and Obesity

Overweight/Obesity
Moon (Guangzhou) Biotechnology Co., Ltd.200 enrolled1 locationNCT07331974
Recruiting

ASSESSMENT OF THE NATURAL HISTORY AND PROGNOSTIC FACTORS OF THERAPEUTIC RESPONSE IN SUB-PHENOTYPES OF PATIENTS WITH OBESITY: THE BOLOBE STUDY

Overweight/ObesityObese Adults
IRCCS Azienda Ospedaliero-Universitaria di Bologna10,000 enrolled1 locationNCT07666425
Recruiting
Phase 1

Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants

Overweight/Obesity
Beijing QL Biopharmaceutical Co.,Ltd60 enrolled1 locationNCT07550816
Recruiting
Not Applicable

SucroMet Nutritional Intervention Trial

Glucose metabolismOverweight/Obesity
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud120 enrolled1 locationNCT07656298
Recruiting
Phase 1

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of IBIO-600 in Overweight or Obese Adults

Overweight/Obesity
iBio, Inc.32 enrolled1 locationNCT07487376
Recruiting
Not Applicable

Smartwatch-based Intervention for Cardiovascular Health (SWITCH)

PrediabetesPrehypertensionOverweight/Obesity+1 more
Beijing Anzhen Hospital1,400 enrolled3 locationsNCT07372729
Recruiting
Not Applicable

BfedBwell INSPIRE Pilot

Cancer SurvivorshipOverweight/Obesity
University of Colorado, Denver25 enrolled1 locationNCT07446595
Recruiting
Phase 1

A Study of Zovaglutide (ZT002 Injection) in Participants With Impaired Kidney Function and Healthy Participants

Overweight/Obesity
Beijing QL Biopharmaceutical Co.,Ltd40 enrolled3 locationsNCT07443059
Recruiting
Phase 2

MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity

Insulin ResistancePrediabetesOverweight/Obesity
Hudson Biotech120 enrolled1 locationNCT07505745
Recruiting
Not Applicable

Comparing Outcomes Among Children With Obesity in a Community Healthy Lifestyle Program

Pediatric ObesityOverweight/ObesityPediatric Overweight
University of Texas Southwestern Medical Center160 enrolled1 locationNCT07342855
Recruiting
Not Applicable

Snacking Effects on the Brain Response to Foods and Satiety During Dieting

Overweight/Obesity
University of Colorado, Denver70 enrolled1 locationNCT07428187
Recruiting
Not Applicable

Effects of Cranberry on Gut and Metabolic Health

Insulin ResistanceMetabolic SyndromeMicrobiota+1 more
Laval University73 enrolled1 locationNCT07460856
Recruiting
Not Applicable

High Phenolic Olive Oil for Enhancing Metabolic Health: a Randomized-controlled Trial in Patients With cEntral Obesity (HOPE)

Overweight/ObesityAdultsMetabolic Abnormalities+1 more
University of Peloponnese80 enrolled1 locationNCT07445503
Recruiting
Phase 1

Bioequivalence Study of BGM0504 Injection

Overweight/Obesity
BrightGene Bio-Medical Technology Co., Ltd.144 enrolled1 locationNCT07382908
Recruiting
Not Applicable

Asiaticoside for Treating Overweight/Obesity

Overweight/Obesity
Shanghai Zhongshan Hospital30 enrolled1 locationNCT07241533
Recruiting
Not Applicable

Immediate Effect of Whole-Body Vibration on Cardiovascular Response and Functional Capacity in Overweight/Obese Young Women

Overweight/Obesity
Cairo University26 enrolled1 locationNCT07263243
Recruiting
Not Applicable

WeArable teChnology daTa driVen digitAl healTh cOachINg (ACTIVATION)- A Mixed-methods Study

HypertensionType 2 Diabetes Mellitus (T2DM)Prediabetes+3 more
Alexandra Hospital1,700 enrolled1 locationNCT06752772
Recruiting
Not Applicable

Effect of Low Valine Diet on Body Weight and Metabolic Parameters

Metabolic Associated Fatty Liver DiseaseMetabolic DiseasesOverweight/Obesity
Shanghai Zhongshan Hospital48 enrolled1 locationNCT06883578
Recruiting
Phase 4

Effects of Testosterone Undecanoate vs Placebo on Intrahepatic Fat Content in Overweight/Obese Men With T2DM or Prediabetes and Hypogonadism

Hypogonadism, MaleFatty LiverOverweight/Obesity+1 more
Alexandra Kautzky-Willer32 enrolled1 locationNCT03851627
Recruiting

A pilot gender-sensitised lifestyle intervention for overweight men targeted at physical activity, diet, and mental health

Overweight/ObesityMental Well-being
University of Technology Sydney90 enrolled1 locationACTRN12620000266965