RecruitingACTRN12617000925347

Comparison of the oral microorganisms between patients being treated with orthodontic brackets or aligners.

Difference in the oral microbiota of patients being treated with clear aligners and brackets: a clinical trial

Sponsor

University of Melbourne, School of Dentistry

Enrollment

120 participants

Start Date

May 16, 2017

Study Type

Interventional

Conditions

Gingivitis White spot lesions

Summary

This research will compare the individual bacterial taxa between 2 orthodontic appliances, the fixed self-ligating bracket system and Invisalign clear aligners. The association of individual taxa and the presence or absence of white spot lesions and gingivitis for both orthodontic techniques will be analysed.

Eligibility

Sex: Both males and femalesMin Age: 11 Yearss

Inclusion Criteria4

There is less than 8mm of crowding.
Patients have all permanent teeth present, except third molars and any necessary orthodontic extractions.
Demonstrate ability to maintain adequate oral hygiene.
Show optimum dental health without the immediate need for restorations.

Exclusion Criteria8

Skeletal anterior-posterior discrepancies between the maxilla and mandible (ANB below or equal to 5).
Centric relation (CR)- Centric occlusion (CO) discrepancies of greater than 3mm.
Anterior or posterior open bite.
Patients who are pregnant, diabetic, using mouth rinses or taking medications, including antibiotic therapy.
Presence of impacted teeth.
Presence of pre-treatment white spot lesions.
Presence of developmental defects of enamel i.e. Amelogenesis imperfecta, hypomineralisation.
Presence of active periodontal disease as evidenced by attachment loss.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

Clear orthodontic aligners (Invisalign) to move teeth. Test subjects- 60 participants will be treated orthodontically using Invisalign aligners. The aligners are to be worn 22 hours per day. Plaque

Clear orthodontic aligners (Invisalign) to move teeth. Test subjects- 60 participants will be treated orthodontically using Invisalign aligners. The aligners are to be worn 22 hours per day. Plaque samples will be taken and analysed prior to the start of treatment and at 6 months of treatment. Presence of white spot tooth lesions and gingivitis will be assessed at these 2 time periods. The aligners will be prescribed and inserted by orthodontic postgraduate students under the supervision of fully qualified orthodontic specialists, or by orthodontists at private orthodontic practices.