Gingivitis Clinical Trials

44 recruitingLast updated: May 21, 2026

There are 44 actively recruiting gingivitis clinical trials across 23 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4. Top locations include Pavia, Lombardy, Italy, Shanghai, Shanghai Municipality, China, Aydin, Turkey (Türkiye). Updated daily from ClinicalTrials.gov.


Gingivitis Trials at a Glance

44 actively recruiting trials for gingivitis are listed on ClinicalTrialsFinder across 6 cities in 23 countries. The largest study group is Not Applicable with 26 trials, with the heaviest enrollment activity in Pavia, Shanghai, and Aydin. Lead sponsors running gingivitis studies include University of Pavia, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University, and Abant Izzet Baysal University.

Browse gingivitis trials by phase

About Gingivitis Clinical Trials

Looking for clinical trials for Gingivitis? There are currently 48 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Gingivitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Gingivitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 44 trials

Recruiting
Not Applicable

Evaluation of the Effect of the Toothpaste on Delicate Gums

Gingivitis
Lacer S.A.60 enrolled1 locationNCT07494747
Recruiting

Association Between Periodontal Status and the Prevalence of Entamoeba Gingivalis and Trichomonas Tenax

PeriodontitisGingivitis and Periodontal Diseases
Abant Izzet Baysal University120 enrolled1 locationNCT07551115
Recruiting

Development of A Self-Assessment Tool for Personalized Preventive Periodontal Care Among the Saudi Population Using Semi-Supervised Learning

GingivitisPeriodontal DiseasesPeriodontitis
Universiti Sains Malaysia393 enrolled1 locationNCT07410351
Recruiting

ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE

GingivitisPeriodontal DiseasesPeriodontitis
Abant Izzet Baysal University160 enrolled1 locationNCT07530978
Recruiting

Diagnostic Accuracy of Oral Images, OPGs, Biomarkers and Questionnaires vs. Clinical Assessment for Periodontal Disease (PostNCT07164573)

GingivitisPeriodontitisPeriodontal Disease
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University2,000 enrolled3 locationsNCT07406867
Recruiting
Not Applicable

Is Professional Tooth Cleaning Necessary for Managing Gingivitis (Gingival Inflammation) if Subjects Use Intelligent Toothbrushes?

GingivitisPeriodontitis
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University92 enrolled1 locationNCT07549347
Recruiting
Not Applicable

Effect of Morus Nigra Mouthwash on Gingivitis Treatment

Gingivitis
Inonu University30 enrolled1 locationNCT07499596
Recruiting
Not Applicable

Evaluation of Safety and Efficacy of Bixdo Ultra Compact Water Flosser

Plaque-induced gingivitis
Tufts University165 enrolled1 locationNCT06352645
Recruiting

Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues

GingivitisPeriodontitis
University of Pisa40 enrolled2 locationsNCT06480825
Recruiting
Not Applicable

Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis

Gingival bleedingplaqueMicrobiome+2 more
Kenvue Brands LLC250 enrolled1 locationNCT07501455
Recruiting
Not Applicable

Mobile Application Push Notification in Improving Oral Hygiene Behaviour in Adolescent Orthodontic Patients

Dental Plaque and GingivitisOral Hygiene Reinforcement During Fixed Orthodontic Treatment
Kumeran A/L Mohan78 enrolled1 locationNCT07288853
Recruiting
Not Applicable

Evaluation of Toothbrush Bristles

Gingivitis and Periodontal Diseases
State University of New York at Buffalo70 enrolled1 locationNCT07306026
Recruiting
Not Applicable

NOVOSYN® Quick Versus MONOSYN® Quick Suture Material in Resective Periodontal Surgery

GingivitisPeriodontal DiseasesGingival Diseases
Aesculap AG84 enrolled1 locationNCT05813236
Recruiting
Not Applicable

Effectiveness of Coenzyme Q10 and Probiotics in Periodontal Therapy During Pregnancy

PregnancyMicrobiotaGingivitis+4 more
University of Pavia40 enrolled1 locationNCT07029360
Recruiting
Not Applicable

Lactoferrin-Based Oral Care for Periodontal Health in Pregnancy

PregnancyGingivitisOral Microbiota+1 more
University of Pavia40 enrolled1 locationNCT07069140
Recruiting
Phase 4

6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health

GingivitisDental Plaque Accumulation
Colgate Palmolive90 enrolled1 locationNCT07414173
Recruiting
Not Applicable

Effectiveness of Intraseptal Anesthesia for Periodontal Surgical Procedures

PeriodontitisGingivitis and Periodontal Diseases
University of Belgrade60 enrolled1 locationNCT07212270
Recruiting
Not Applicable

The Antiplaque and Antigingivitis Effect of Pure Green Tea Mouth Wash Compared to Placebo and Essential Oils Mouth Washes

Gingival bleedingGingival inflammationGingivitis+3 more
King Abdullah University Hospital44 enrolled1 locationNCT07364565
Recruiting
Not Applicable

Effect of Probiotics on the Periodontal Status of Orthodontic Patients

GingivitisPeriodontal Health
University Hospital, Lille116 enrolled1 locationNCT04634201
Recruiting

HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy

Periodontal DiseasesPeriodontitisGingivitis; Chronic
Ömer Faruk Okumuş180 enrolled1 locationNCT07312045