Gingivitis Clinical Trials

49 recruitingLast updated: July 11, 2026

There are 49 actively recruiting gingivitis clinical trials across 24 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4. Top locations include Pavia, Lombardy, Italy, Shanghai, Shanghai Municipality, China, Fort Wayne, Indiana, United States. Updated daily from ClinicalTrials.gov.


Gingivitis Trials at a Glance

49 actively recruiting trials for gingivitis are listed on ClinicalTrialsFinder across 6 cities in 24 countries. The largest study group is Not Applicable with 27 trials, with the heaviest enrollment activity in Pavia, Shanghai, and Fort Wayne. Lead sponsors running gingivitis studies include University of Pavia, Colgate Palmolive, and Abant Izzet Baysal University.

Browse gingivitis trials by phase

Treatments under study

About Gingivitis Clinical Trials

Looking for clinical trials for Gingivitis? There are currently 52 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Gingivitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Gingivitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 49 trials

Recruiting

Salivary Biomarkers in Periodontal Disease Progression

PeriodontitisPeriodontal DiseaseGingivitis and Periodontal Diseases
Suleyman Demirel University240 enrolled1 locationNCT07661784
Recruiting
Not Applicable

Intraoral Scanners as Periodontal and Dental Pathologies Diagnosis Tools

DiagnosisGingivitisPeriodontitis+1 more
CHU de Reims30 enrolled1 locationNCT06006429
Recruiting

Evaluation of Gingival Crevicular Fluid Cytokine Profiles in Children and Young Adults With Gingivitis

Gingivitis
Nigde Omer Halisdemir University80 enrolled1 locationNCT07607639
Recruiting
Not Applicable

The Effect of Vitamin D Supplementation on the Anti-inflammatory Response in Periodontal Diseases

GingivitisPeriodontal DiseasesVitamin D Deficiency
Recep Tayyip Erdogan University Training and Research Hospital120 enrolled1 locationNCT07636733
Recruiting
Phase 2Phase 3

Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial

developmental delayGingivitisPeriodontitis+2 more
University of Washington6,000 enrolled1 locationNCT07424846
Recruiting
Phase 4

Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High Gingivitis

plaqueGingivitis
Colgate Palmolive100 enrolled1 locationNCT07614490
Recruiting
Not Applicable

Evaluation of the Effect of the Toothpaste on Delicate Gums

Gingivitis
Lacer S.A.60 enrolled1 locationNCT07494747
Recruiting

Association Between Periodontal Status and the Prevalence of Entamoeba Gingivalis and Trichomonas Tenax

PeriodontitisGingivitis and Periodontal Diseases
Abant Izzet Baysal University120 enrolled1 locationNCT07551115
Recruiting

Development of A Self-Assessment Tool for Personalized Preventive Periodontal Care Among the Saudi Population Using Semi-Supervised Learning

GingivitisPeriodontal DiseasesPeriodontitis
Universiti Sains Malaysia393 enrolled1 locationNCT07410351
Recruiting

ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE

GingivitisPeriodontal DiseasesPeriodontitis
Abant Izzet Baysal University160 enrolled1 locationNCT07530978
Recruiting

Diagnostic Accuracy of Oral Images, OPGs, Biomarkers and Questionnaires vs. Clinical Assessment for Periodontal Disease (PostNCT07164573)

GingivitisPeriodontitisPeriodontal Disease
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University2,000 enrolled3 locationsNCT07406867
Recruiting
Not Applicable

Is Professional Tooth Cleaning Necessary for Managing Gingivitis (Gingival Inflammation) if Subjects Use Intelligent Toothbrushes?

GingivitisPeriodontitis
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University92 enrolled1 locationNCT07549347
Recruiting
Not Applicable

Effect of Morus Nigra Mouthwash on Gingivitis Treatment

Gingivitis
Inonu University30 enrolled1 locationNCT07499596
Recruiting
Not Applicable

Evaluation of Safety and Efficacy of Bixdo Ultra Compact Water Flosser

Plaque-induced gingivitis
Tufts University165 enrolled1 locationNCT06352645
Recruiting

Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues

GingivitisPeriodontitis
University of Pisa40 enrolled2 locationsNCT06480825
Recruiting
Not Applicable

Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis

Gingival bleedingplaqueMicrobiome+2 more
Kenvue Brands LLC250 enrolled1 locationNCT07501455
Recruiting
Not Applicable

Mobile Application Push Notification in Improving Oral Hygiene Behaviour in Adolescent Orthodontic Patients

Dental Plaque and GingivitisOral Hygiene Reinforcement During Fixed Orthodontic Treatment
Kumeran A/L Mohan78 enrolled1 locationNCT07288853
Recruiting
Not Applicable

Evaluation of Toothbrush Bristles

Gingivitis and Periodontal Diseases
State University of New York at Buffalo70 enrolled1 locationNCT07306026
Recruiting
Not Applicable

NOVOSYN® Quick Versus MONOSYN® Quick Suture Material in Resective Periodontal Surgery

GingivitisPeriodontal DiseasesGingival Diseases
Aesculap AG84 enrolled1 locationNCT05813236
Recruiting
Not Applicable

Lactoferrin-Based Oral Care for Periodontal Health in Pregnancy

PregnancyGingivitisOral Microbiota+1 more
University of Pavia40 enrolled1 locationNCT07069140