CompletedPhase 2ACTRN12617001540303

Steroids To Reduce the Impact on DElirium study (STRIDE)

Steroids To Reduce the Impact on DElirium (STRIDE) study - pilot randomised controlled trial of preoperative dexamethasone to prevent delirium after hip fracture.


Sponsor

Waitemata District Health Board

Enrollment

80 participants

Start Date

Nov 14, 2018

Study Type

Interventional

Conditions

Summary

This randomised, placebo-controlled, double-blind clinical trial will include 80 patients aged 65 and over admitted for hip fracture.


Eligibility

Sex: Both males and femalesMin Age: 65 Yearss

Inclusion Criteria2

  • years and older
  • Fractured neck of femur

Exclusion Criteria6

  • Dementia or any cognitive deficit
  • Delirium on admission
  • Used steroids in the last 7 days
  • Significant and poorly controlled diabetes (glucose >12 mmol/l on admission)
  • Systemic infection
  • Unable to read and speak English

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Interventions

Dexamethasone (20mg) intravenous infusion delivered once (as early as possible after acute admission to hospital)

Dexamethasone (20mg) intravenous infusion delivered once (as early as possible after acute admission to hospital)


Locations(1)

Auckland, New Zealand

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