RecruitingACTRN12623000299606

Determining the effectiveness of Sambucol in reducing the duration and symptoms of the common cold in children and teens


Sponsor

Pharmacare Pty Ltd

Enrollment

198 participants

Start Date

Jun 19, 2023

Study Type

Observational

Conditions

Summary

This is an observational tele trial to determine the effectiveness of Sambucol in the management of the symptoms of the common cold and flu-like illnesses in children and adolescents aged between 2 years and 17 years who are already committed to consuming Sambucol as part of their own routine self-care (with parental consent and monitoring). Sambucol Black Elderberry Cold & Flu is a liquid that has an extract of Elderberry that is safe for children and teens to consume to help relieve their cold and flu symptoms. This same Elderberry extract has been shown to be useful in helping to resolve cold and flu symptoms like coughing, sneezing and headaches in adults. This study is testing if the same extract in Sambucol Black Elderberry Cold & Flu is useful for children and adolescents with cold and flu symptoms or not. The study will be conducted online via a study app and will measure the duration and severity of cold symptoms of participants who are taking Sambucol Black Elderberry Cold & Flu, until the illness resolves. The researchers expect that Sambucol will significantly reduce the severity of the symptoms of the common cold in comparison to existing data on children with cold and flu symptoms. It is also expected that Sambucol will reduce the severity of the symptoms of the common cold in children comparable to reductions observed in clinical trials with adults taking Sambucol, and significantly greater than adults taking placebo.


Eligibility

Sex: Both males and femalesMin Age: 2 YearssMax Age: 17 Yearss

Plain Language Summary

Simplified for easier understanding

The common cold is one of the most frequent illnesses in childhood, causing runny noses, sore throats, coughs, and general misery. While most colds resolve on their own, parents are always looking for safe, natural ways to help their children feel better sooner. Sambucol is a liquid product made from black elderberry extract that has shown promise in reducing cold and flu symptoms in adults. This observational study is looking at whether Sambucol has the same benefits for children and teenagers. Children aged 2 to 17 whose parents have already decided to use Sambucol as part of their child's cold management are invited to track their symptoms using a study app until the illness resolves. There is no placebo or comparison group — this is an observational study measuring how symptoms change over time in children taking Sambucol, compared to existing data from adults. Your child may be eligible if they are between 2 and 17 years old, are generally healthy, started their cold within the last 72 hours, have at least one cold symptom, and you as their parent or guardian are willing to consent. Children who are already taking antibiotics, antihistamines, or other regular medications, or who have asthma, diabetes, or immune conditions would not be eligible.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Eligible participants, who are aged 2-17 years, have parental consent to take part, currently are experiencing cold and/or flu-like symptoms and consuming Sambucol for the treatment of these symptoms,

Eligible participants, who are aged 2-17 years, have parental consent to take part, currently are experiencing cold and/or flu-like symptoms and consuming Sambucol for the treatment of these symptoms, will be asked to report their symptoms, severity and consumption of Sambucol until their symptoms resolve. Duration will vary but participation is expected to be between 2 and 15 days, until cold and flu-like symptoms have subsided, or 15 days has lapsed. Information will be collected using a purpose-built study app “Sambucol Research”. The app contains a daily (once a day at the same time of day) survey for participants to report: - Personal details including name, age and address - Symptoms of cold and flu - Severity of their symptoms - How often and how much Sambucol they consume The Sambucol product isn’t being administered by researchers however, we will collect information about consumption during participation. As part of the daily surveys, participants will indicate frequency and amount of Sambucol consumed for a period of between 2-15 days (until cold and flu-like symptoms have subsided or 15 days has lapsed). Parents of children who are aged 10 or under will provide this information via the study app. Those aged over 10 will provide the information on the study app themselves, under parental supervision.


Locations(1)

ACT,NSW,NT,QLD,SA,TAS,WA,VIC, Australia

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ACTRN12623000299606


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