Cold Clinical Trials

4 recruiting

About Cold Clinical Trials

Looking for clinical trials for Cold? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cold trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cold clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Phase 3

A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)

Chronic Inducible UrticariaCold UrticariaSymptomatic Dermographism+1 more
Celldex Therapeutics240 enrolled72 locationsNCT07266402
Recruiting
Not Applicable

Energy Dense Fueling for Cold-Weather Operations

Cold Exposure
United States Army Research Institute of Environmental Medicine8 enrolled1 locationNCT07489690
Recruiting
Not Applicable

Circadian Rhythm Deregulation in Patients With CAPS

Cryopyrin Associated Periodic SyndromeFamilial Cold UrticariaMuckle-Wells Syndrome+1 more
Hospices Civils de Lyon30 enrolled6 locationsNCT06544018
Recruiting
Phase 1

A Phase 1 Study of GTX-B001 in Healthy Subjects and Patients With Chronic Inducible Urticaria

Healthy SubjectsChronic Inducible UrticariaCold Urticaria+1 more
Granular Therapeutics Limited72 enrolled2 locationsNCT07181369
Recruiting
Not Applicable

Effect of Caffeine on Cold-stimulated Brown Adipose Tissue Activity

Cold ExposureBrown Adipose Tissue (BAT) Physiology
University Hospital, Basel, Switzerland12 enrolled1 locationNCT06978777
Recruiting

Cold Agglutinin Disease Real World Evidence Registry

Cold Agglutinin Disease (CAD)Cold Agglutinin Syndrome (CAS)
RECORDATI GROUP400 enrolled68 locationsNCT05791708
Recruiting
Phase 1

OM336 in Autoimmune Cytopenias

ITP - Immune ThrombocytopeniaAIHA - Warm Autoimmune Hemolytic AnemiaAIHA - Cold Autoimmune Hemolytic Anemia
Ouro Medicines32 enrolled3 locationsNCT07083960
Recruiting
Not Applicable

The Effects of Cold-water Immersion on Exercise Performance Recovery and Postprandial Plasma Aminoacidemia

Sport RecoveryAminoacidemiaCold-water Immersion
McGill University12 enrolled1 locationNCT06698237
Recruiting
Not Applicable

Intermittent Cold Exposure and Brown Adipose Tissue Hyperplasia

Cold ExposureBrown Adipose Tissue18F-FDG PET/CT
University of Edinburgh12 enrolled1 locationNCT07048405
Recruiting

National Longitudinal Cohort of Hematological Diseases- Autoimmune Hemolytic Anemia

AIHA - Warm Autoimmune Hemolytic AnemiaAIHA - Cold Autoimmune Hemolytic AnemiaAutoimmune Hemolytic Anemia Mixed Type
Institute of Hematology & Blood Diseases Hospital, China9,999 enrolled1 locationNCT07019038
Recruiting

An Examination of Brown Adipose Tissue and Energy Expenditure in Infants

Cold Induced Thermogenesis
Pennington Biomedical Research Center60 enrolled1 locationNCT05517967
Recruiting
Not Applicable

Reforça't: A Community, Social, and Healthcare Program for Patients With Cardiorespiratory Conditions Upon Hospital Discharge

Heart FailureChronic Obstructive Lung Disease (COLD)
Corporació de Salut del Maresme i la Selva200 enrolled1 locationNCT06897410
Recruiting
Not Applicable

Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure

Cold Exposure
Indiana University30 enrolled1 locationNCT05822141
Recruiting
Not Applicable

Thermogenic Silencer Regulatory Factors in Humans

ObesityMetabolic DiseaseCold Exposure
Rockefeller University120 enrolled1 locationNCT06424132
Recruiting
Not Applicable

Effects of Cold Atmospheric Plasma (CAP) on Peritoneal Tumor Tissue

Peritoneal TumorCold Atmospheric Plasma (CAP)J-Plasma
University Hospital, Ghent5 enrolled1 locationNCT06796634
Recruiting
Not Applicable

Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery

ColdPain SyndromeVomiting+4 more
Zhejiang Cancer Hospital132 enrolled1 locationNCT06704698
Recruiting

Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia

Myelodysplastic SyndromesImmune ThrombocytopeniaAutoimmune Hemolytic Anemia+3 more
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico200 enrolled1 locationNCT05931718
Recruiting
Not Applicable

Thermotherapy in Acute Nonspecific Neck Pain

ColdNeck Pain
Acibadem University60 enrolled2 locationsNCT06507761
Recruiting
Phase 2

Beetroot Juice NO Cold Study

Respiratory Tract InfectionsCold SymptomsExhaled Nitric Oxide
Southern Methodist University150 enrolled2 locationsNCT06416228
Recruiting

Immunological Reaction of the Recipient After Cold-stored Saphenous Venous Allograft (Bioprotec)

AllograftSaphenous VeinCold Temperature
Centre Hospitalier Universitaire de Nīmes50 enrolled1 locationNCT05096351