Comparison of broccoli sprout extracts in non-pregnant and pregnant women

Sulforaphane is a natural compound found in broccoli sprout supplements that may have anti-inflammatory and antioxidant benefits, including potential applications in pregnancy complications. However, different commercial broccoli sprout products vary widely in how they are made, meaning the amount of active sulforaphane that reaches the bloodstream can differ significantly between brands. This study will compare three commercially available broccoli sprout extract products to measure how much sulforaphane each one delivers into the blood, and whether this differs between non-pregnant women, healthy pregnant women, and pregnant women with a hypertensive disorder (such as pre-eclampsia). You may be eligible if you are female and 18 or older, and fall into one of three groups: a healthy non-pregnant woman; a healthy pregnant woman between 28 and 36 weeks; or a pregnant woman between 28 and 36 weeks who has been diagnosed with a hypertensive disorder of pregnancy. You would not be eligible if you currently take broccoli sprout supplements, have allergies to broccoli, have significant pregnancy complications beyond hypertension (for groups 2 and 3), or are enrolled in another nutrition-related clinical trial.