Preeclampsia Clinical Trials

85 recruitingLast updated: May 4, 2026

Preeclampsia Trials at a Glance

91 actively recruiting trials for preeclampsia are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 21 trials, with the heaviest enrollment activity in New York, Iowa City, and Barcelona. Lead sponsors running preeclampsia studies include Anna Stanhewicz, PhD, Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, and Monash Health.

Browse preeclampsia trials by phase

Treatments under study

About Preeclampsia Clinical Trials

Looking for clinical trials for Preeclampsia? There are currently 85 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Preeclampsia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Preeclampsia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 91 trials

Recruiting
Phase 2

Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia

PregnancyPreeclampsia (PE)
University of Mississippi Medical Center60 enrolled1 locationNCT02989025
Recruiting
Not Applicable

MitoQ to Improve Vascular Funciton in Preeclampsia

PregnancyPreeclampsia
Medical College of Wisconsin80 enrolled1 locationNCT07229261
Recruiting
Phase 2

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Preeclampsia
Mayo Clinic14 enrolled1 locationNCT06333652
Recruiting

The Combined First Trimester Screening

Fetal Growth RestrictionPreterm LaborPreeclampsia (PE)+4 more
Institute of Health Information and Statistics of the Czech Republic2,000 enrolled3 locationsNCT07015203
Recruiting

Exercise Testing After Preeclampsia

HypertensionPreeclampsiaHeart Failure Preserved Ejection Fraction
Vanderbilt University Medical Center500 enrolled1 locationNCT06741436
Recruiting

Preeclampsia: Origin, Characteristics and Effects on Mother and Baby

PregnancyPreeclampsia (PE)
Medical University of Graz250 enrolled1 locationNCT07513558
Recruiting
Not Applicable

Vagal Stimulation Therapy and Preeclampsia

PreeclampsiaGestational Hypertension
Fundación Internacional René Mey210 enrolled4 locationsNCT06953115
Recruiting

Molecular Study of the Maternal-fetal Interface in Preeclampsia.

Preeclampsia
Carlos Simon Foundation2,084 enrolled5 locationsNCT06232668
Recruiting
Not Applicable

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

PreeclampsiaObstructive Sleep Apnea of AdultObstetrical Complications
The George Washington University Biostatistics Center1,500 enrolled14 locationsNCT03487185
Recruiting
Phase 2

Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories

PreeclampsiaGestational Hypertension
Massachusetts General Hospital204 enrolled3 locationsNCT07041281
Recruiting
Phase 3

PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia

Preeclampsia
Lina Bergman294 enrolled17 locationsNCT06033131
Recruiting

Dietary Salicylates and Preeclampsia

PreeclampsiaDiet HabitPregnancy Disease
Poznan University of Life Sciences500 enrolled1 locationNCT06239363
Recruiting
Not Applicable

Impact of First-trimester Preeclampsia Screening on Perinatal and Maternal Morbidity (RANSPRE)

Preeclampsia (PE)
Assistance Publique - Hôpitaux de Paris14,500 enrolled22 locationsNCT05521776
Recruiting

Placental Imaging Techniques

PregnancyUltrasoundPregnancy Outcomes+5 more
Carilion Clinic60 enrolled1 locationNCT06861309
Recruiting

Prevention of Preeclampsia in Denmark: A National Implementation Study

Preeclampsia (PE)
Copenhagen University Hospital at Herlev80,000 enrolled3 locationsNCT07485140
Recruiting
Phase 2

Statin Intervention for Severe Early-Onset Placental Insufficiency. (STATIN-PRE Trial)

Intrauterine Growth Restriction (IUGR)Preeclampsia (PE)Placental Insufficiency
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau154 enrolled2 locationsNCT07098975
Recruiting
Early Phase 1

Vascular Effects of High-Salt After Preeclampsia

PreeclampsiaPreeclampsia Postpartum
Anna Stanhewicz, PhD40 enrolled1 locationNCT06749418
Recruiting

Effects of High Altitude on AMPK Activation

PregnancyPreeclampsiaIUGR
University of Colorado, Denver84 enrolled1 locationNCT02391519
Recruiting

Non-Invasive Preeclampsia Screening and Biobank

Preeclampsia (PE)
Sequenom, Inc.6,550 enrolled21 locationsNCT06643741
Recruiting
Not Applicable

Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy

PreeclampsiaHypertensive Disorder of Pregnancy
IRCCS Azienda Ospedaliero-Universitaria di Bologna400 enrolled1 locationNCT05999851