The CAMAS Study: A Cross-sectional magnetic resonance imaging study on the myocardial effects of long-term anaerobic exercise using structure-function correlation
A Cross-sectional magnetic resonance imaging study on the myocardial effects of long-term anaerobic exercise using structure-function correlation in active adults
The University of Sydney
40 participants
Jan 27, 2026
Observational
Conditions
Summary
The CAMAS study is a prospective, longitudinal observational cohort study examining the effects of long-term anaerobic exercise on myocardial structure and function. Adults with predominantly anaerobic gym training are compared with individuals undertaking predominantly aerobic exercise using cardiac magnetic resonance imaging (CMR) and electrocardiography. Blood samples are collected for exploratory molecular analyses where funding permits. Participants are followed annually for up to ten years to document cardiac diagnoses and cardiovascular events. The study aims to identify imaging-based phenotypes associated with anaerobic exercise and potential cardiovascular risk.
Eligibility
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Interventions
The CAMAS study is a prospective, longitudinal observational exposure study (no intervention). Participants are enrolled based on exercise exposure: a) Exposure group (anaerobic): adults (at least 18 years) with approximately 5 years of predominantly anaerobic gym training (at least 3 days/week, at least 120 min/week, including at least 1 lower body session/week); anaerobic group additionally requires ability to bench press and squat at least their body weight (kg). All enrolled participants undergo a baseline research assessment comprising a questionnaire (anticipated to take approximately 10-15 minutes); 12-lead digital ECG, venous blood sampling, and cardiac MRI (CMR) (approximately 1 hour). Participants are followed annually for up to 10 years to capture interim cardiac diagnoses and cardiovascular events.
Locations(1)
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ACTRN12626000308392