Tezspire Cardiac Events PASS

This post-approval safety study is monitoring for potential heart-related events in patients with severe asthma who are being treated with tezepelumab (Tezspire) compared to those on other intensive standard asthma therapies. Researchers are collecting real-world data to ensure the long-term safety profile of this medication. **You may be eligible if...** - You are 12 years or older - You have a diagnosis of severe asthma - You are currently receiving tezepelumab (Tezspire) or another intensive standard-of-care treatment for severe asthma **You may NOT be eligible if...** - You have less than 12 months of medical records available before your treatment start date - You have a history of congenital heart disease or heart transplant - You have had a heart attack or stroke in the 180 days before starting treatment Talk to your doctor to see if this trial is right for you.