RecruitingNCT00345553

Biliary Atresia Study in Infants and Children

Biliary Atresia Study in Infants and Children (BASIC)

Sponsor

Arbor Research Collaborative for Health

Enrollment

1,265 participants

Start Date

May 16, 2006

Study Type

OBSERVATIONAL

Conditions

Biliary Atresia

Summary

Little is known about the factors that cause biliary atresia nor the factors that influence disease progression. The purpose of this study is to collect the pertinent clinical information, genetic material and body fluid samples to enable investigators to address the following aims: To identify the gene or genes implicated in the etiology of BA; To characterize the natural history of the older, non-transplanted child with BA.

Eligibility

Min Age: 6 MonthsMax Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This long-term study follows children and young adults with biliary atresia (BA), a serious liver disease in infants where the bile ducts are blocked or absent. Researchers track disease progression and outcomes in patients who still have their native liver, aiming to better understand how the disease evolves over time. You may be eligible if: - You have a confirmed diagnosis of biliary atresia - You are between 6 months and 20 years old - You still have your native liver (have not had a liver transplant) - You or your parent/guardian is willing to provide informed consent You may NOT be eligible if: - You are currently enrolled in the ChiLDReN PROBE study - Your biliary atresia diagnosis cannot be confirmed through medical records - You have had a liver transplant - Your family is unable or unwilling to attend all scheduled visits Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(16)

Children's Hospital of Los Angeles

Los Angeles, California, United States

University of California at San Francisco

San Francisco, California, United States

Children's Hospital Colorado

Aurora, Colorado, United States

Children's Healthcare of Atlanta - Emory University

Atlanta, Georgia, United States

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States

Riley Children's Hospital

Indianapolis, Indiana, United States

Johns Hopkins School of Medicine

Baltimore, Maryland, United States

Washington University School of Medicine

St Louis, Missouri, United States

Mount Sinai Medical Center

New York, New York, United States

Children's Hospital Medical Center

Cincinnati, Ohio, United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

UPMC Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, United States

Texas Children's Hospital (Baylor College of Medicine)

Houston, Texas, United States

University of Utah

Salt Lake City, Utah, United States

Seattle Children's Hospital

Seattle, Washington, United States

Hospital for Sick Children

Toronto, Ontario, Canada

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NCT00345553

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