Hirschsprung Disease Genetic Study
Genetic Analysis of Hirschsprung Disease
NYU Langone Health
3,000 participants
Jan 1, 2001
OBSERVATIONAL
Conditions
Summary
Hirschsprung disease is a genetic condition caused by lack of nerve cells in varying lengths of the intestines. This study will investigate the complex genetic basis of the disease, which involves multiple interacting genetic factors.
Eligibility
Inclusion Criteria1
- \- Individuals with Hirschsprung disease and their first degree relatives (any segment length of disease, with or without other congenital anomalies or health problems, single or multiple affected individuals in family)
Exclusion Criteria2
- Unable or unwilling to provide sample for genetic studies
- Individual, parent, or guardian unable to comprehend and provide informed consent
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Interventions
Blood, saliva, or DNA samples are requested from all study participants. The blood or saliva samples are used to isolate DNA in all participants. Blood samples are also used to establish cell lines in some participants.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT00478712