RecruitingNot ApplicableNCT07519915

Improvement of Understanding of Pediatric Sacral Neuromodulation: Therapeutic Strategies and Outcome Variables

Stimulation Modeling and Adaptive Response Tracking in Pediatric Gastrointestinal Motility Disorders

Sponsor

Friedrich-Alexander-Universität Erlangen-Nürnberg

Enrollment

25 participants

Start Date

Jul 1, 2018

Study Type

INTERVENTIONAL

Conditions

Hirschsprung Disease Constipation - Functional Gastrointestinal Motility Disorders in Children

Summary

The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders. By combining advanced neuroimaging, patient-specific biophysical modeling, electrophysiological characterization, and clinical translation, the SMART-GUT project establishes a comprehensive framework to systematically investigate neuromodulation in this pediatric population. This integrative approach enables a direct link between mechanism, targeting, and clinical outcome.

Eligibility

Min Age: 3 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called SNM/MRI/EMG for people with constipation - functional, gastrointestinal motility disorders in children, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 3 Years to 18 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURESNM/MRI/EMG

Participants are receiving clinical baseline evaluation, preoperative sacral and functional MRI, reconstruction of digital twin, surgical implantation of sacral neuromodulation including intraoperative testing, postoperative sacral and functional MRI, and clinical follow-up