RecruitingPhase 3NCT00796263

Antiretroviral Therapy for Acute and Chronic HIV Infection

Sponsor

SEARCH Research Foundation

Enrollment

900 participants

Start Date

May 13, 2009

Study Type

INTERVENTIONAL

Conditions

Acute HIV Infection Chronic HIV Infection

Summary

The purpose for this protocol is to provide safe and effective standard ART to SEARCH 010 and SEARCH 013 participants. Participants are enrolled in an acute HIV infection study (SEARCH 010 protocol: 'Establish and characterize an acute HIV infection cohort in a Thai high-risk population') or in a study of chronic HIV infection (SEARCH 013 protocol 'Characteristics of immunity in gut mucosa, spinal fluid, lymph node and blood of HIV negative and HIV positive Thais').

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is providing HIV treatment (antiretroviral therapy) to people in Thailand with either newly acquired or long-term HIV infection, to study how treatment affects the immune system and viral suppression. **You may be eligible if...** - You are 18 years or older - You are already enrolled in related HIV studies (SEARCH 010 or 013) with confirmed HIV-1 infection - You are choosing to start or continue antiretroviral treatment (HIV medication) - You are willing to attend follow-up visits and can give consent **You may NOT be eligible if...** - You have a medical or psychiatric condition that would prevent you from safely following the study protocol Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGHAART

1 (lamivudine) or 2 (lamivudine + abacavir) nuceloside/nucleotide analog reverse-transcriptase inhibitor (NRTI) class medications once daily plus dolutegravir(DTG) 50 mg orally once daily