RecruitingNCT01034033

Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples

Sponsor

Stanford University

Enrollment

3,300 participants

Start Date

Aug 1, 2001

Study Type

OBSERVATIONAL

Conditions

Breast Cancer Gynecologic Cancers Ovarian Cancer Ovarian/Peritoneal/Fallopian Cancer

Summary

The purpose of this study is to try to understand the biology of development of breast, ovarian, fallopian tube, peritoneal or endometrial cancer from persons at high genetic risk for these diseases. The influence of environmental factors on cancer development in individuals and families will be studied. The efficacy of treatments for these diseases will be evaluated.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting tissue and genetic information from women with BRCA or other inherited gene mutations that greatly increase the risk of breast or ovarian cancer, in order to better understand how these cancers develop and to improve early detection and prevention strategies. **You may be eligible if...** - You are a woman with a known inherited gene mutation (BRCA1, BRCA2, PTEN, CDH1, or TP53) that significantly raises your risk of breast or ovarian cancer - You have a strong family history of breast or ovarian cancer, even without a confirmed gene mutation - You are scheduled for surgery to investigate a pelvic mass (lump or growth) that appears suspicious for cancer on imaging **You may NOT be eligible if...** - There are no additional specific exclusion criteria listed beyond the above requirements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.