RecruitingNCT01580982

Molecular Analysis of Oncogenes and Resistance Mechanisms in Lung Cancer

Molecular Analysis of Oncogenes and Resistance Mechanisms in Lung and Other Thoracic Cancers

Sponsor

University of Colorado, Denver

Enrollment

500 participants

Start Date

Jan 23, 2012

Study Type

OBSERVATIONAL

Conditions

Lung Neoplasms

Summary

The mechanisms of sensitivity and resistance to oncogene-targeted therapy can be determined from tumor tissue or tumor cell lines derived from available archival samples and/or from standard-of-care re-biopsy upon suspected tumor progression.

Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study is analyzing tumor tissue and blood samples from lung cancer patients — particularly those whose cancer has specific genetic mutations — to understand how cancers become resistant to targeted drug treatments and to help develop better therapies. **You may be eligible if...** - You are 18 or older - You have a thoracic (chest or lung) cancer being treated with drugs that target specific genetic mutations - You are undergoing or scheduled for a standard medical procedure (such as a biopsy, fluid drainage, or surgery) as part of your regular care, and samples can be collected during that procedure **You may NOT be eligible if...** - You are not undergoing any procedure from which samples can be collected - You do not have a thoracic cancer - You are unable to provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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