RecruitingNCT01619553

Genetic Analysis of Keloids

Identification of Genetic Variants That Contribute to Keloid Formation in Families and Isolated Cases.


Sponsor

UConn Health

Enrollment

7,000 participants

Start Date

Apr 1, 2009

Study Type

OBSERVATIONAL

Conditions

Summary

Keloids have a strong genetic component. The goal of this study is to identify genes and regulatory elements on chromosomes that are the cause for keloids or contribute to keloid scarring.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is investigating the genetic causes of keloids — scars that grow beyond the borders of a wound and can be itchy, tender, or painful. Researchers are looking for specific gene mutations or DNA variations that may explain why some people develop keloids and others do not. People eligible to participate must have keloids themselves, or be an unaffected family member of someone with keloids. Participation involves providing a saliva sample, answering questions about your keloids, having photos taken, and potentially donating a small piece of scar tissue if you undergo keloid surgery. This summary was prepared to help patients understand the study in plain language.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

University of Connecticut Health Center (UCHC)

Farmington, Connecticut, United States

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NCT01619553


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