A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma

This study tests whether CyberKnife radiosurgery — a robotic, non-invasive form of radiation that precisely targets tumors — can effectively treat early-stage kidney cancer (renal cell carcinoma) without the need for surgery. **You may be eligible if...** - You have been diagnosed with Stage I kidney cancer (confined to the kidney, no spread) with a tumor no larger than 8 cm - You are 18 or older and able to have MRI or CT imaging - You are in reasonably good health (ECOG performance status 2 or less) - You have at least a 12-month life expectancy - You have not had another cancer in the past 2 years (non-invasive skin cancers are okay) - Your blood counts and kidney function are within acceptable limits **You may NOT be eligible if...** - You have a bleeding disorder that cannot be corrected (preventing a small marker implant in the kidney) - You have had previous radiation to the upper abdomen - You have had another invasive cancer within the past 2 years - The tumor cannot be precisely targeted with CyberKnife due to imaging or tissue limitations Talk to your doctor to see if this trial is right for you.