Feasibility Study for Fibroblast Autologous Skin Grafts

This study tests autologous fibroblast therapy — using a patient's own skin cells to create a personalized skin graft treatment. Small biopsies of healthy skin are taken, fibroblast cells are grown in the lab, and then injected back into the patient's skin to test safety and feasibility of this regenerative approach. You may be eligible if... - You are between 18 and 65 years old - You have healthy skin as assessed by the study team - You are in good overall health with no significant laboratory abnormalities - If female and of childbearing potential, you agree to use contraception and avoid pregnancy during the study You may NOT be eligible if... - You have received an investigational drug in the past 30 days - You have an allergy to local anesthetic, DMSO, human albumin, bovine products, or hetastarch - You are pregnant, lactating, or trying to become pregnant - You have a history of keloid formation - You have an active non-healing wound - You have HIV, hepatitis B or C, HTLV I/II, autoimmune skin diseases, active skin conditions, or uncontrolled diabetes - You are an active smoker or on chronic immunosuppressive medications Talk to your doctor to see if this trial is right for you.