RecruitingNot ApplicableNCT06921707

Pilot Trial for WounDx™ Clinical Decision Support Tool

SC2i-WounDx-001-WounDx™ Pilot Trial: Proof of Concept Feasibility for the Clinical Operations of WounDx™ in Aiding Clinicians Identify Wounds That Are Ready For Surgical Closure


Sponsor

Henry M. Jackson Foundation for the Advancement of Military Medicine

Enrollment

40 participants

Start Date

Mar 21, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital. The WounDx device is experimental and not yet approved by the United States Food and Drug Administration (FDA). WounDx uses information about a patient's wound to generate a report that a surgeon may use to help determine when to close or not close the wound. The final decision to close the wound remains with the surgeon. The results from this pilot trial will inform a larger pivotal trial.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria3

  • Wound surface area ≥75cm 2
  • Extremity injury (including shoulder and buttock - without visceral communication)
  • Wound amenable to Negative Pressure Wound Therapy using 3M™ V.A.C. ® canisters without gel pack

Exclusion Criteria6

  • Insulin Dependent Diabetes
  • Peripheral Vascular Disease
  • Connective Tissue Disorders
  • Preexisting immunosuppressive conditions or immunosuppression therapy
  • Pregnancy
  • Prisoners

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Interventions

DEVICEClinical Decision Support Tool

WounDx is a clinical decision support tool that will help augment the clinicians' judgment regarding the wounds readiness to close.

PROCEDUREStandard of Care (SOC)

The standard of care consists of serial wound irrigation, negative pressure wound therapy, and surgical debridement


Locations(5)

University of Alabama - Birmingham Hospital

Birmingham, Alabama, United States

Emory University / Grady Memorial Hospital

Atlanta, Georgia, United States

Indiana University Health University Hospital

Indianapolis, Indiana, United States

Duke University Hospital

Durham, North Carolina, United States

Brooke Army Medical Center

Fort Sam Houston, Texas, United States

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NCT06921707


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