RecruitingNCT02014389

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

Objective Perimetry in Normal Subjects,Glaucoma Patients and Retinal Dystrophy Patients

Sponsor

Sheba Medical Center

Enrollment

200 participants

Start Date

Dec 1, 2013

Study Type

OBSERVATIONAL

Conditions

Retinitis Pigmentosa Glaucoma Retinal Dystrophies

Summary

Objective perimetry can better monitor visual field defects in retinal dystrophy and Glaucoma patients than conventional subjective perimetry. The PLR ( Pupil Light Reflex to short and long wavelength stimuli should be significantly lower compared to healthy participants in areas of visual field defects in retinal dystrophy and Glaucoma patients.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria3

Age 18-80 years old.
Signing informed consent.
Pupillary reflex to light.

Exclusion Criteria20

Cloudy corneas.
Surgical intraocular ophthalmic procedure within the past 30 days.
No reactive pupils.
Synechia of the iris to the lens after surgery or inflammation.
Neovascularization.
Axenfeld-Rieger Syndrome.
Iris atrophy (ICE syndrome).
Iris coloboma.
Sphincter damage due to ischemia.
Sphincter damage due to trauma (tears of sphincter or diffuse damage to muscle).
Sphincter damage due to Herpes Zoster Uveitis.
Sphincter damage due to high intraocular pressure.
Iris tumor or cyst.
Ectropion uvae.
Adie's pupil.
Third nerve aberrant regeneration of the iris sphincter.
RP patients with Optic neuropathy with the potential of producing a positive RAPD (Relative Afferent Pupillary Defect).
Chronic use of myotics or mydriatics.
Systemic medication that have affect on pupillary reflex .
Any condition preventing accurate measurement or examination of the pupil.