Glaucoma Clinical Trials

124 recruiting

Glaucoma Trials at a Glance

183 actively recruiting trials for glaucoma are listed on ClinicalTrialsFinder across 6 cities in 63 countries. The largest study group is Not Applicable with 91 trials, with the heaviest enrollment activity in Baltimore, Philadelphia, and Palo Alto. Lead sponsors running glaucoma studies include Stanford University, Duke University, and Glaukos Corporation.

Browse glaucoma trials by phase

Treatments under study

About Glaucoma Clinical Trials

Looking for clinical trials for Glaucoma? There are currently 124 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Glaucoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Glaucoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 183 trials

Recruiting

Study to Learn More About Safety of Aflibercept Injection in Japanese Patients With Neovascular Glaucoma (NVG)

Neovascular Glaucoma
Bayer480 enrolled1 locationNCT04519619
Recruiting
Not Applicable

Comparing XEN®-63 Gel Stent and PRESERFLO® MicroShunt

GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Universitaire Ziekenhuizen KU Leuven166 enrolled3 locationsNCT07359547
Recruiting
Phase 4

24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients

Open Angle GlaucomaOcular Hypertension
Mayo Clinic30 enrolled1 locationNCT07325240
Recruiting
Not Applicable

Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus Tonometry

GlaucomaOcular Hypertension
Sensimed AG12 enrolled1 locationNCT04024293
Recruiting
Phase 1Phase 2

Topical Infliximab in Eyes With Penetrating Keratoplasty

Glaucoma Following Surgery
Centre hospitalier de l'Université de Montréal (CHUM)50 enrolled1 locationNCT05180994
Recruiting
Not Applicable

The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston Keratoprosthesis

GlaucomaEye DiseasesCornea Disease
Centre hospitalier de l'Université de Montréal (CHUM)20 enrolled1 locationNCT04232982
Recruiting
Not Applicable

Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

Age-Related Macular DegenerationDiabetic RetinopathyCataract+2 more
University of Copenhagen460 enrolled2 locationsNCT07015034
Recruiting
Not Applicable

Defining Retinal Structures Using Hyperspectral Retinal Imaging

Age-Related Macular DegenerationDiabetic RetinopathyGlaucoma
Center for Eye Research Australia1,000 enrolled1 locationNCT07555574
Recruiting

DSLT for Reducing Medication in Glaucoma

Ocular HypertensionPrimary Open Angle Glaucoma
The Eye Institute of West Florida60 enrolled1 locationNCT07390890
Recruiting

Change in IOP Fluctuation After DSLT

Glaucoma
Ophthalmology Associates, Fort Worth40 enrolled1 locationNCT07428668
Recruiting
Not Applicable

Glaucoma Screening to Enhance At-Risk Californians' Health

Glaucoma
University of California, San Francisco2,000 enrolled2 locationsNCT06854198
Recruiting

IOP Reduction in Pigmentary Glaucoma Using DSLT

Pigmentary Dispersion GlaucomaPigmentary Dispersion Syndrome
Mann Eye Institute45 enrolled1 locationNCT07281391
Recruiting

Glaucoma Related Quality of Life

Glaucoma
Marc Toeteberg-Harms5,000 enrolled1 locationNCT07510087
Recruiting
Not Applicable

Efficacy and Safety of the ELIOS Laser in Combined Cataract and Glaucoma Surgery

Glaucoma
Hôpital Privé de la Baie46 enrolled1 locationNCT06760169
Recruiting
Phase 2Phase 3

Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension

OAG - Open-Angle GlaucomaOHT - Ocular Hypertension
Qlaris Bio, Inc.60 enrolled1 locationNCT07354516
Recruiting
Phase 2

Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension

Glaucoma
Bausch & Lomb Incorporated228 enrolled14 locationsNCT07168902
Recruiting
Phase 3

Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

Glaucoma
Glaukos Corporation510 enrolled1 locationNCT07495852
Recruiting
Not Applicable

A Trial of Hydrus Microstent Versus Goniotomy

GlaucomaGlaucoma, Open-Angle
Massachusetts Eye and Ear Infirmary243 enrolled1 locationNCT06289491
Recruiting
Not Applicable

Preserflo MicroShunt Versus Trabeculectomy

GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Medical University of Bialystok100 enrolled1 locationNCT07496957
Recruiting
Not Applicable

Advancing Pediatric Retinal Imaging With Auto-aligned OCT

Retinal DiseaseGlaucomaOptic Nerve Diseases+1 more
Duke University50 enrolled1 locationNCT06841575