Glaucoma Clinical Trials

86 recruiting

Frequently Asked Questions

Common questions about Glaucoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 173 trials

Recruiting
Phase 2Phase 3

Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension

OAG - Open-Angle GlaucomaOHT - Ocular Hypertension
Qlaris Bio, Inc.36 enrolled1 locationNCT07354516
Recruiting

Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options

Open Angle GlaucomaGlaucoma EyeClosed-Angle Glaucoma+2 more
Hospices Civils de Lyon132 enrolled1 locationNCT07303257
Recruiting

Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

GlaucomaOcular Surface Disease
University of California, Los Angeles75 enrolled1 locationNCT04354545
Recruiting
Not Applicable

Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle Glaucoma

GlaucomaPrimary Open Angle GlaucomaPseudoexfoliation Glaucoma+2 more
Okuvision GmbH50 enrolled1 locationNCT06682962
Recruiting
Not Applicable

Aqueous Humor and Ocular Tissue Analysis in Glaucoma and Cataract

CataractPrimary Open Angle Glaucoma (POAG)
Military Institute od Medicine National Research Institute40 enrolled2 locationsNCT07462000
Recruiting
Phase 1

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

Open-angle Glaucoma (OAG)NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)
Life Biosciences Inc.18 enrolled2 locationsNCT07290244
Recruiting
Not Applicable

Automated Applanation Tonometry - Updated

GlaucomaGlaucoma, Suspect
Duke University200 enrolled1 locationNCT07298356
Recruiting

Alcon Hydrus Stent Implantation - Long Term Follow up After 8 Years

Glaucoma
Johannes Gutenberg University Mainz200 enrolled1 locationNCT07460791
Recruiting
Not Applicable

Community Based Treatment for (ComBaT) Glaucoma

Glaucoma
University of Michigan60 enrolled2 locationsNCT06124521
Recruiting
Phase 4

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

Open Angle GlaucomaGlaucomaOcular Hypertension+1 more
University of Miami20 enrolled1 locationNCT07217678
Recruiting

UBM Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle Glaucoma

Primary Open Angle Glaucoma (POAG)
Minia University Hospital30 enrolled1 locationNCT07454447
Recruiting
Not Applicable

Modified Trabeculectomy After Failure of Combined Phaco With GATT

Glaucoma
Assiut University20 enrolled1 locationNCT07455786
Recruiting

Study to Learn More About Safety of Aflibercept Injection in Japanese Patients With Neovascular Glaucoma (NVG)

Neovascular Glaucoma
Bayer480 enrolled1 locationNCT04519619
Recruiting
Phase 2Phase 3

Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

Glaucoma
Glaukos Corporation610 enrolled3 locationsNCT07075718
Recruiting
Not Applicable

Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea

ObesityObstructive Sleep ApneaPrimary Open Angle Glaucoma
Cairo University40 enrolled1 locationNCT07447011
Recruiting

Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg

Ocular Hypertension (OH)Open-angle Glaucoma (OAG)
Glaukos Corporation30 enrolled1 locationNCT07400926
Recruiting
Not Applicable

Clinical Trial to Evaluate the Safety and Effectiveness of a Canaloplasty Device in Subjects With Open-Angle Glaucoma

OAG - Open-Angle Glaucoma
New World Medical, Inc.70 enrolled3 locationsNCT05696561
Recruiting
Phase 3

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Primary Open Angle Glaucoma
AbbVie130 enrolled21 locationsNCT06822738
Recruiting
Phase 2

Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

Normal Tension Glaucoma (NTG)Non-proliferative Diabetic Retinopathy (NPDR)Open-angle Glaucoma (OAG)
Qlaris Bio, Inc.14 enrolled1 locationNCT07354477
Recruiting

To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value in Improving Postoperative Outcomes.

CataractGlaucoma
The New York Eye & Ear Infirmary150 enrolled1 locationNCT07425496