Glaucoma Clinical Trials

217 recruitingLast updated: June 18, 2026

There are 217 actively recruiting glaucoma clinical trials across 64 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1. Top locations include Philadelphia, Pennsylvania, United States, Palo Alto, California, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Glaucoma Trials at a Glance

217 actively recruiting trials for glaucoma are listed on ClinicalTrialsFinder across 6 cities in 64 countries. The largest study group is Not Applicable with 108 trials, with the heaviest enrollment activity in Philadelphia, Palo Alto, and Boston. Lead sponsors running glaucoma studies include Glaukos Corporation, Stanford University, and Duke University.

Browse glaucoma trials by phase

Treatments under study

About Glaucoma Clinical Trials

Looking for clinical trials for Glaucoma? There are currently 136 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Glaucoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Glaucoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 217 trials

Recruiting
Not Applicable

Comparative Effectiveness and Safety of ELIOS in Patients With Open-Angle Glaucoma Undergoing Cataract Surgery

Open Angle Glaucoma
Elios Vision, Inc.194 enrolled16 locationsNCT06246136
Recruiting
Phase 3

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

Primary Open Angle Glaucoma
AbbVie130 enrolled24 locationsNCT06822738
Recruiting
Phase 4

Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension

GlaucomaOcular Hypertension
Indiana University50 enrolled1 locationNCT07588152
Recruiting
Not Applicable

A Study Evaluating the Safety and Efficacy of MINIject S+ in Subjects With Open Angle Glaucoma

Glaucoma
iSTAR Medical60 enrolled5 locationsNCT07009236
Recruiting
Not Applicable

Hydrus® Microstent New Enrollment Post-Approval Study

Primary Open Angle Glaucoma
Alcon Research545 enrolled22 locationsNCT04553523
Recruiting
Not Applicable

Village-Integrated Eye Worker Trial II

Age-Related Macular DegenerationDiabetic RetinopathyGlaucoma
University of California, San Francisco60,200 enrolled1 locationNCT03752840
Recruiting

Study to Learn More About Safety of Aflibercept Injection in Japanese Patients With Neovascular Glaucoma (NVG)

Neovascular Glaucoma
Bayer480 enrolled1 locationNCT04519619
Recruiting
Phase 4

Travoprost Intraocular Implant + iStent Infinite

Glaucoma, Open-Angle
Glaukos Corporation150 enrolled1 locationNCT06066645
Recruiting

PRESERFLO™ MicroShunt XI Observational PMCF Study With no Control Group

Primary Open Angle Glaucoma
Santen SAS112 enrolled11 locationsNCT07235592
Recruiting
Phase 4

Rocklatan vs Latanoprost Post-DSLT

Glaucoma
Eye Centers of Southeast Texas36 enrolled1 locationNCT07465913
Recruiting
Phase 1

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

Open-angle Glaucoma (OAG)NAION( Non-arteritic Anterior Ischemic Optic Neuropathy)
Life Biosciences Inc.18 enrolled4 locationsNCT07290244
Recruiting
Not Applicable

Additive Efficacy of Physical Activity Program in Hypthyroidism Elder Females With Glaucoma and Fatty Liver Issues

Non-Alcoholic Fatty Liver DiseaseSubclinical hypothyroïdismPrimary Open Angle Glaucoma
Cairo University40 enrolled1 locationNCT07599241
Recruiting
Not Applicable

Morphometric Markers of the Effectiveness of Micropulse Cyclophotocoagulation

Glaucoma
Kazakh Eye Research Institute20 enrolled1 locationNCT07592923
Recruiting
Not Applicable

Tear Interleukin Biomarkers After Glaucoma Treatment

Glaucoma
Kazakh Eye Research Institute24 enrolled1 locationNCT07592988
Recruiting

Choroidal and Retinal Features in PACD and POAG on OCT and OCTA

GlaucomaOCTAChoroid
Zhongshan Ophthalmic Center, Sun Yat-sen University132 enrolled1 locationNCT07580014
Recruiting
Not Applicable

Adaptive Optics Retinal Imaging

Glaucoma, Primary Open Angle
Food and Drug Administration (FDA)150 enrolled1 locationNCT05370287
Recruiting
Not Applicable

Comparison of Intraocular Pressure Measurement With the Novel TonoVera Device With Other Commonly Used Devices

Glaucoma
State University of New York at Buffalo300 enrolled1 locationNCT05523622
Recruiting
Not Applicable

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

Open-angle Glaucoma (OAG)Ocular Hypertension (OHT)
Medical University of South Carolina172 enrolled1 locationNCT07408154
Recruiting
Not Applicable

Comparing XEN®-63 Gel Stent and PRESERFLO® MicroShunt

GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Universitaire Ziekenhuizen KU Leuven166 enrolled3 locationsNCT07359547
Recruiting
Phase 1Phase 2

GVB-2001 Gene Therapy Via Intracameral Injection for the Treatment of Primary Open Angle Glaucoma

Primary Open Angle Glaucoma (POAG)
IVIEW Therapeutics Inc.6 enrolled1 locationNCT06921317