RecruitingPhase 3NCT02025023

Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study


Sponsor

University of Washington

Enrollment

120 participants

Start Date

Dec 1, 2013

Study Type

INTERVENTIONAL

Conditions

Summary

Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called 5-fluorouracil Injection, a procedure called Incision and Curettage, and others for people with chalazion. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG5-fluorouracil Injection

If the chalazion is present at follow-up visit, another injection of 5-FU will be given.

DRUGTriamcinolone Acetonide

If chalazion present at follow-up, another Triamcinolone injection will be done.

PROCEDUREIncision and Curettage

If chalazion present at follow-up visit, patient will be randomized to receive local injection of either triamcinolone, 5-FU, or triamcinolone/5-FU mixture.

DRUGTriamcinolone Acetonide/5-fluorouracil mixture

If chalazion persists at follow-up visit, another injection of triamcinolone/5-FU mixture will be done.


Locations(1)

University of Washington Eye Institute at Harborview

Seattle, Washington, United States

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NCT02025023


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