RecruitingPhase 1NCT02390635

PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemia

PET/MR, PET/CT and Whole Body MR in Newly Diagnosed Acute Myeloid Leukemia (AML)


Sponsor

M.D. Anderson Cancer Center

Enrollment

77 participants

Start Date

Jul 15, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

This pilot phase I trial studies how well positron emission tomography (PET)/magnetic resonance imaging (MRI), fludeoxyglucose F-18 (18F-FDG) PET/computed tomography (CT), and whole body MRI work in finding extramedullary myeloid leukemia in patients with newly diagnosed acute myeloid leukemia. Extramedullary myeloid leukemia is a type of cancer found outside of the bone marrow and can be hard to detect with routine bone marrow monitoring, such as bone marrow aspirations. Diagnostic procedures, such as PET/MRI, 18F-FDG PET/CT and whole body MRI, may help find and diagnose extramedullary myeloid leukemia in patients with newly diagnosed acute myeloid leukemia.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Computed Tomography, a procedure called Diffusion Weighted Imaging, and others for people with acute myeloid leukemia and acute promyelocytic leukemia with pml-rara. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREComputed Tomography

Undergo 18F-FDG PET/CT

PROCEDUREDiffusion Weighted Imaging

Undergo whole body PET/MRI

RADIATIONFludeoxyglucose F-18

Undergo 18F-FDG PET/CT

DRUGGadolinium

Given IV

PROCEDUREMagnetic Resonance Imaging

Undergo whole body PET/MRI

PROCEDUREPositron Emission Tomography

Undergo 18F-FDG PET/CT and whole body PET/MRI

PROCEDUREThree-Dimensional Spoiled Gradient MRI

Undergo whole body PET/MRI


Locations(1)

M D Anderson Cancer Center

Houston, Texas, United States

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NCT02390635


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