MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Master Screening and Reassessment Protocol (MSRP) for the NCI MyeloMATCH Clinical Trials
National Cancer Institute (NCI)
2,000 participants
Jun 18, 2024
INTERVENTIONAL
Conditions
Summary
This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participants' ability to register to clinical trials throughout the course of their myeloid cancer (acute myeloid leukemia or myelodysplastic syndrome) treatment. This study involves testing patients' bone marrow and blood for certain biomarkers. A biomarker (sometimes called a marker) is any molecule in the body that can be measured. Doctors look at markers to learn what is happening in the body. Knowing about certain markers can give doctors more information about what is driving the cancer and how to treat it. Testing patients' bone marrow and blood will show doctors if patients have markers that specific drugs can target. The marker testing in this study will let doctors know if they can match patients with a treatment study (myeloMATCH clinical trial) that tests treatment for the type of cancer they have or continue standard of care treatment with their doctor on the Tier Advancement Pathway (TAP).
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Given IV
Given IV or SC
Receive SOC treatment
Undergo biopsy
Undergo collection of blood, urine, and/or buccal swab samples
Undergo bone marrow aspiration
Undergo bone marrow biopsy
Given IV
Undergo chest x-ray
Undergo CT
Given
Given IV
Given PO
Undergo ECHO
Given PO
Given PO
Given SC
Given IV
Given IV
Given PO
Given IV
Given SC
Given IV
Undergo MUGA
Undergo rapid genetic testing
Given PO
Given PO
Undergo PET
Undergo total body irradiation
Given PO
Locations(346)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05564390