RecruitingNot ApplicableNCT02421705

Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)

Visceral Sensitivity in IBD and IBS: Role of Inflammation, Immune Activity and Genetic Factors


Sponsor

KU Leuven

Enrollment

99,999,999 participants

Start Date

Feb 1, 2010

Study Type

INTERVENTIONAL

Conditions

Summary

Aim: More insight in pathogenesis of IBS and IBD. Samples are collected in context of an European research project.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying how sensitive the gut is to pain and discomfort in people with irritable bowel syndrome (IBS), inflammatory bowel disease (such as Crohn's disease or ulcerative colitis), or in people with no gut problems at all. You may be eligible if: you have been diagnosed with IBS, active ulcerative colitis, ulcerative colitis in remission, active Crohn's disease, or Crohn's disease in remission — or if you are a healthy person with no stomach pain; and you are willing to stop certain gut medications at least 24 hours before the study visit. You may NOT be eligible if: you have a serious kidney or liver disease, thyroid problems, or clotting issues; or you have had abdominal surgery (other than a simple, uncomplicated appendix removal). Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSample collection

Collection of blood, feces samples, sample of nasal mucosa and biopsies (rectum and colon descendens), questionnaires and performance of rectal sensitivity measurement (barostat), MR scan of brain and transit measurement of colon


Locations(1)

University Hospitals Leuven

Leuven, Vlaams-Brabant, Belgium

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NCT02421705


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