RecruitingNot ApplicableNCT02502162

Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome


Sponsor

Stanford University

Enrollment

120 participants

Start Date

Jun 1, 2015

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators are testing treatment with low-dose naltrexone (LDN) for symptom relief of complex regional pain syndrome (CRPS). Study participants will be randomly assigned to receive either LDN or placebo for a period of several weeks. During this period participants will be asked to attend either in-person or virtual study visits and complete questionnaires.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria4

  • Upper and/or lower extremity CRPS
  • On stable treatment for 1 month
  • CRPS for at least 1 year
  • Meet the Budapest criteria for CRPS at time of the study.

Exclusion Criteria3

  • Any known allergy to naltrexone or naloxone
  • Use of prescription opioid analgesics or illegal opioid use
  • Current or planned pregnancy.

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Interventions

DRUGLDN
DRUGPlacebo

Sugar pill


Locations(1)

Stanford University

Palo Alto, California, United States

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NCT02502162


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