RecruitingNot ApplicableNCT02609685

Active Surveillance of Papillary Thyroid Microcarcinoma


Sponsor

Cedars-Sinai Medical Center

Enrollment

216 participants

Start Date

May 13, 2016

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to better understand the outcomes of active surveillance (observation) instead of immediate surgery, which is the current standard of care for papillary thyroid microcarcinoma (PTMC). Patients with a 1.5 cm or smaller thyroid nodule(s) with papillary thyroid carcinoma will be eligible for the study.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is monitoring patients with very small, low-risk papillary thyroid cancer (tumors 2 cm or smaller) to track how the cancer behaves over time with active observation rather than immediate surgery, to determine whether watchful waiting is a safe approach. **You may be eligible if...** - You have been diagnosed with papillary thyroid cancer confirmed or highly suspected by biopsy or genetic testing (BRAF mutation) - Your thyroid nodule is 2 cm or smaller based on ultrasound - You are able to read and write English fluently - You are willing and able to sign the consent form **You may NOT be eligible if...** - Your thyroid cancer is of a high-grade or poorly differentiated type - You have suspicious lymph nodes in the neck that suggest cancer has spread - Your nodule is in a location that puts nearby structures at risk (such as near the nerve that controls the voice box, or adjacent to the windpipe) - You have a history of radiation to the neck Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERActive Surveillance

Subjects will be actively observed for disease progression (condition worsens) instead of receiving immediate surgery, considered standard of care.


Locations(1)

Cedars-Sinai Medical Center

Los Angeles, California, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT02609685


Related Trials