RecruitingNCT05189821

RFA Treatment for Papillary Thyroid Microcarcinoma

RFA Treatment for Papillary Thyroid Microcarcinoma Cohort


Sponsor

Columbia University

Enrollment

50 participants

Start Date

Nov 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Thyroid surgery has always been the mainstay of treatment for thyroid cancer. Thyroid surgery carries a low risk of complications that include recurrent or superior laryngeal nerve injury leading to voice changes, hypoparathyroidism, hypothyroidism with need for thyroid hormone supplementation, and unsightly scarring. Although many patients with thyroid cancer find these risks acceptable, these risks are sometimes less acceptable to patients with benign disease. In an era when the medical field is treating thyroid diseases less aggressively, there is a pressing need to identify approaches to treat indolent malignant disease less invasively. The purpose of this observational study is to evaluate the efficacy and safety of Radiofrequency Ablation (RFA) for treatment of Papillary Thyroid Microcarcinoma (PTMC) in patients that have already agreed to RFA procedure based on treating physician recommendation. This is a data collection study in which we ask participants to give us access to information generated before and after RFA treatment of their condition. The RFA procedure uses image guidance to place an electrode through the skin into the target tumor. In RFA, high-frequency electrical currents are passed through an electrode, creating a small region of heat to treat the lesion.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Adult patients (>/= 18 years)
  • Biopsy proven papillary thyroid microcarcinoma (>/= 1.5cm in greatest diameter, PTMC)
  • Either refuse surgery or are not good surgical candidates

Exclusion Criteria2

  • Cardiac arrhythmia
  • Pregnancy

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Interventions

PROCEDURERadiofrequency Ablation

Ultrasound guided radiofrequency ablation


Locations(1)

Columbia University

New York, New York, United States

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NCT05189821


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