RecruitingPhase 3NCT02633514

Adjuvant Treatment for Incomplete Resection Thymoma or Thymic Carcinoma

A Randomized Phase III Study of Adjuvant Radiotherapy Versus Adjuvant Radiochemotherapy in Patients With Incomplete ResectionThymoma or Thymic Carcinoma


Sponsor

Fudan University

Enrollment

1 participants

Start Date

Dec 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This study is designed to investigate whether adjuvant radiochemotherapy after incomplete resection has a better survival than adjuvant radiotherapy for thymoma or thymic carcinoma.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at what additional treatments (radiation, chemotherapy, or both) work best after surgery for thymoma or thymic carcinoma (cancers of the thymus gland, a small organ in the chest) when the surgeon was not able to remove the entire tumor. **You may be eligible if...** - You have been diagnosed with thymoma or thymic carcinoma - Your surgery did not completely remove the tumor (called an incomplete resection) - You are in good enough health to receive additional treatment - You have not yet started radiation or chemotherapy after surgery **You may NOT be eligible if...** - Your surgeon was able to remove all visible cancer - You have already received post-surgery radiation or chemotherapy - You have serious medical conditions that would make additional treatment unsafe - You have a different type of chest tumor Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCisplatin

25mg/m2,iv gtt,d1-3

DRUGEtoposide

75mg/m2,iv gtt,d1-3

RADIATIONradiotherapy

60Gy/30Fx


Locations(1)

Kailiang Wu

Shanghai, Shanghai Municipality, China

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NCT02633514


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