RecruitingNCT02634645

TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)

A Multicenter Prospective Study Evaluating Outcomes of Endoscopic Eradication Therapy in Patients With Barrett's Esophagus Associated Neoplasia: The TREAT-BE (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus) Consortium


Sponsor

University of Colorado, Denver

Enrollment

5,000 participants

Start Date

Jan 1, 2015

Study Type

OBSERVATIONAL

Conditions

Summary

A prospective outcomes study in patients with and esophageal cancer (EAC) and Barrett's esophagus (BE) associated neoplasia being evaluated for endoscopic eradication therapy (EET).


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria1

  • Patients with Barrett's related neoplasia and dysplasia. Patients with esophageal cancer

Exclusion Criteria1

  • Patients with squamous cell carcinoma

Interventions

PROCEDUREEndoscopic eradication therapies (EET)

Endoscopic eradication therapies (EET) includes endoscopic mucosal resection (EMR), which describes the process by which the area most likely to harbor highest grade of dysplasia/neoplasia is removed; radiofrequency ablation (RFA), which describes the process by which Barrett's segments are removed via burning/ablation; and cryotherapy.

PROCEDUREEsophagectomy

The esophagus is surgically removed

DRUGChemotherapy

Chemical substances are used to treat cancer

RADIATIONRadiation

Cancer cells are destroyed by radiation therapy.


Locations(4)

UCLA Medical Center

Los Angeles, California, United States

Moffitt Cancer Center

Tampa, Florida, United States

Northwestern Memorial Hospital

Chicago, Illinois, United States

Washington University

St Louis, Missouri, United States

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NCT02634645


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