RecruitingNot ApplicableNCT02747888

Hereditary Risk Factors for Thyroid Cancer


Sponsor

Dana-Farber Cancer Institute

Enrollment

250 participants

Start Date

Mar 1, 2016

Study Type

INTERVENTIONAL

Conditions

Summary

Thyroid cancers can occur sporadically, but can also be found as tumors that cluster in families with other cancers or genetic syndromes. Researchers are studying thyroid cancer in children and families, with a particular interest in understanding genes and other factors that may put individuals at risk for developing thyroid cancer and thyroid nodules. * In this study, family and medical history information is collected alongside a blood or saliva sample for genetic studies. * Individuals with a past or present childhood thyroid cancer/nodule or a thyroid cancer suspected to be inherited in their family are invited to participate.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is investigating whether thyroid cancer (cancer of the butterfly-shaped gland in the neck) can run in families by collecting genetic information from patients and their relatives, aiming to identify inherited risk factors. **You may be eligible if...** - You are a child or adult patient with a current or previous diagnosis — or strong suspicion — of thyroid cancer or a thyroid nodule (lump in the thyroid) - You come from a family where thyroid cancer occurred in childhood, appeared in multiple family members, or is associated with a known genetic syndrome - Adult family members without thyroid cancer may also be eligible if the family pattern suggests hereditary risk **You may NOT be eligible if...** - You do not have thyroid cancer or nodules and your family history does not suggest a hereditary pattern - You are unwilling to participate in genetic testing or provide consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETIC•Referral to Genetic Counselor, if indicated

Locations(1)

Dana Farber Cancer Institute

Boston, Massachusetts, United States

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NCT02747888


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