RecruitingNCT02760108

Parkinson's Families Project


Sponsor

University College, London

Enrollment

2,000 participants

Start Date

Apr 1, 2015

Study Type

OBSERVATIONAL

Conditions

Summary

One person in every 500 has Parkinson's and around 127,000 people are living with the condition in the UK. The aim of the study is to identify new genes that predispose or cause Parkinson's Disease or Parkinsonism. There is a pressing need to study the genetic makeup of family members both with and without Parkinson's. As families share a common genetic background, it is easier to find new Parkinson's genes by studying the genetic makeup of people with Parkinson's alongside other members of their families. We are particularly interested in studying the genetic makeup of two groups of people: 1. those who developed Parkinson's before the age of 45; and 2. those who have a family history of other relatives affected by Parkinson's. By identifying genetic factors that cause Parkinson's, we hope to understand more about the condition. Doing so will lead to the development of better diagnosis, improved disease models, and we hope in time, to the development of better treatment.


Eligibility

Min Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting genetic and medical information from people with Parkinson's disease and their family members to identify inherited gene changes that may increase the risk of developing Parkinson's, particularly in younger patients or those with a family history. **You may be eligible if...** - You have a clinical diagnosis of Parkinson's disease or a related movement disorder (parkinsonism) - You have a family history of Parkinson's disease (a parent, sibling, or grandparent also affected) OR your symptoms began before age 45 - You are a first- or second-degree family member of someone enrolled in the study, whether or not you have Parkinson's yourself - You are over 16 years old **You may NOT be eligible if...** - You do not have the mental capacity to consent to participate in the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(2)

Royal Free London NHS Foundation Trust

London, United Kingdom

University College London Hospitals NHS Foundation Trust

London, United Kingdom

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NCT02760108


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