Parkinson's Disease Clinical Trials

134 recruiting

Parkinson's Disease Trials at a Glance

159 actively recruiting trials for parkinson's disease are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 59 trials, with the heaviest enrollment activity in Beijing, Boston, and Cleveland. Lead sponsors running parkinson's disease studies include VA Office of Research and Development, AbbVie, and Beijing Tiantan Hospital.

Browse parkinson's disease trials by phase

Treatments under study

About Parkinson's Disease Clinical Trials

Looking for clinical trials for Parkinson's Disease? There are currently 134 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Parkinson's Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Parkinson's Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 159 trials

Recruiting
Not Applicable

Deep Brain Stimulation Therapy in Movement Disorders

Parkinson's Disease
National Institute of Neurological Disorders and Stroke (NINDS)300 enrolled1 locationNCT02119611
Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Not Applicable

Auditory Sleep Stimulation or Sham in People With Parkinson Disease Mild Cognitive Impairment During Cognitive Training

Mild Cognitive ImpairmentParkinson's Disease
University of Zurich50 enrolled1 locationNCT07441915
Recruiting
Phase 1

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

DementiaParkinson's Disease
National Institute of Mental Health (NIMH)184 enrolled1 locationNCT04396873
Recruiting
Not Applicable

Deep Brain Stimulation Surgery for Movement Disorders

DystoniaParkinson's DiseaseEssential Tremor
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT01581580
Recruiting
Not Applicable

Personalized rTMS Protocol Based on Functional Reserve to Enhance Ambulatory Function in PD Patients

Parkinson's Disease and Parkinsonism
Samsung Medical Center60 enrolled1 locationNCT06350617
Recruiting
Phase 1

SAD Study in Patients With Parkinson's Disease and Motor Fluctuations

PARKINSON DISEASE (Disorder)Advanced Parkinson's Disease
Serina Therapeutics40 enrolled6 locationsNCT07422675
Recruiting
Not Applicable

Non-invasive VNS for Parkinson's Gait

Parkinson's Disease
VA Office of Research and Development40 enrolled1 locationNCT06562569
Recruiting
Phase 1Phase 2

rTMS to Improve Cognition in Parkinson's

Mild Cognitive ImpairmentParkinson's Disease
VA Office of Research and Development56 enrolled2 locationsNCT03836950
Recruiting
Phase 1

Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients

Parkinson DiseaseParkinson's Disease
Innopeutics Corporation6 enrolled1 locationNCT07371338
Recruiting

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

Parkinson's Disease
Bayer300 enrolled5 locationsNCT07330258
Recruiting

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

Parkinson's Disease
Boston Scientific Corporation1,500 enrolled84 locationsNCT02071134
Recruiting
Phase 2

Ketamine for Veterans With Parkinson's Disease

Parkinson's Disease
VA Office of Research and Development80 enrolled1 locationNCT06231563
Recruiting

A Study to Assess Change in Sleep Disturbances of Adult Participants With Advanced Parkinson's Disease Receiving Subcutaneous Foslevodopa/Foscarbidopa

Advanced Parkinson's Disease
AbbVie103 enrolled14 locationsNCT07284342
Recruiting

A Study to Assess Change in Disease Symptoms in Adult Participants With Advanced Parkinson Disease Using Subcutaneous Foslevodopa/Foscarbidopa in Belgium

Parkinson's Disease
AbbVie120 enrolled10 locationsNCT07382440
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Parkinson's Disease
Hoffmann-La Roche900 enrolled101 locationsNCT07174310
Recruiting
Phase 2

A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease

Parkinson's Disease (PD)
GEN İlaç ve Sağlık Ürünleri A.Ş.45 enrolled1 locationNCT07322887
Recruiting
Not Applicable

Electrophysiology-based DBS Programming for PD

Parkinson's Disease (PD)
University of Florida30 enrolled1 locationNCT07348705
Recruiting
Not Applicable

Blood Flow Restriction for Optimizing Balance in Parkinson's Disease

Parkinson's Disease and Parkinsonism
The University of Texas Health Science Center at San Antonio20 enrolled1 locationNCT06508801
Recruiting

Natural History Protocol for Movement Disorders

TremorParkinson's DiseaseMovement Disorder
National Institute of Neurological Disorders and Stroke (NINDS)4,000 enrolled1 locationNCT05413291