RecruitingNot ApplicableNCT02808572

New Biomarkers of Bone Mineral Metabolism as Cardiovascular Risk Factors in Chronic Kidney Disease Patients

New Biomarkers of Bone and Mineral Metabolism as Risk Factors for Morbidity/Mortality in Chronic Kidney Disease Patients Not Requiring Dialysis


Sponsor

University Hospital, Montpellier

Enrollment

250 participants

Start Date

Mar 12, 2013

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate the relationships between bone mineral metabolism markers (osteoprotegerin, fibroblast growth factor 23) at inclusion and the occurence of cardiovascular events during a 7 year follow-up.


Eligibility

Min Age: 18 YearsMax Age: 95 Years

Inclusion Criteria2

  • Patient who has signed the written consent form
  • Patient with chronic renal failure defined by glomerular filtration rate (GFR) but without dialysis therapy

Exclusion Criteria2

  • Pregnancy
  • Patient with chronic renal failure requiring dialysis therapy

Interventions

BIOLOGICALPlasma osteoprotegerin level

dosage of plasma osteoprotegerin

BIOLOGICALPlasma fibroblast growth factor 23 level

dosage of plasma fibroblast growth factor 23

PROCEDUREVascular calcification score

measurement of vascular calcification score by multidetection computerized tomography


Locations(7)

AIDER

Montpellier, France

CHU Montpellier, Cardiology department

Montpellier, France

CHU Montpellier, Endocrinology department

Montpellier, France

CHU Montpellier, Intensive care unit

Montpellier, France

CHU Montpellier, Internal medicine department

Montpellier, France

CHU Montpellier, Nephrology department

Montpellier, France

AIDER

Saint-Jean-de-Védas, France

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NCT02808572


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