RecruitingPhase 4NCT02922894

Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury

Sponsor

John D. Dingell VA Medical Center

Enrollment

100 participants

Start Date

Jun 9, 2017

Study Type

INTERVENTIONAL

Conditions

Sleep Apnea Spinal Cord Injury

Summary

This study will investigate potential therapeutic approaches for sleep-disordered breathing (SDB) in patients with chronic cervical spine injury (\>6 months post-injury).

Eligibility

Min Age: 18 YearsMax Age: 89 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Acute episodic hypoxia, a drug called Placebo, and others for people with sleep apnea and spinal cord injury. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 89 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREAcute episodic hypoxia

The subjects will undergo 30 minutes of baseline monitoring followed by 15 episodes of one minute of episodic hypoxia with supplemental CO2 to maintain isocapnia. This is followed by a 45 minute recovery period.

PROCEDURESupplemental oxygen

Supplemental oxygen therapy for 6 weeks

DRUGTrazodone

100mg before bedtime

DRUGPlacebo

One placebo pill before-bedtime

PROCEDURESham

Room air will be administered instead of episodic hypoxia or supplemental oxygen..