Sleep Apnea Clinical Trials

323 recruitingLast updated: June 18, 2026

There are 323 actively recruiting sleep apnea clinical trials across 48 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4, Phase 3, Early Phase 1. Top locations include Philadelphia, Pennsylvania, United States, Beijing, Beijing Municipality, China, Detroit, Michigan, United States. Updated daily from ClinicalTrials.gov.


Sleep Apnea Trials at a Glance

323 actively recruiting trials for sleep apnea are listed on ClinicalTrialsFinder across 6 cities in 48 countries. The largest study group is Not Applicable with 146 trials, with the heaviest enrollment activity in Philadelphia, Beijing, and Detroit. Lead sponsors running sleep apnea studies include VA Office of Research and Development, Chinese University of Hong Kong, and Brigham and Women's Hospital.

Browse sleep apnea trials by phase

Treatments under study

About Sleep Apnea Clinical Trials

Looking for clinical trials for Sleep Apnea? There are currently 50 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sleep Apnea trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sleep Apnea clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 323 trials

Recruiting
Not Applicable

Treatment Failure of Continuous Positive Airway Pressure (CPAP) in Patients With Obstructive Sleep Apnea Syndrome (OSA): A Trial Comparing Polysomnography and the Sunrise Device to Drive Treatment-Adjustment Decisions.

Sleep Apnea Syndrome, Obstructive
University Hospital, Grenoble105 enrolled1 locationNCT07530302
Recruiting
Not Applicable

Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation

Sleep-disordered breathing (SDB)Obstructive Sleep ApneaArrhythmia+3 more
Beijing Anzhen Hospital658 enrolled27 locationsNCT07444372
Recruiting

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

Pediatric Obstructive Sleep Apnea
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)120 enrolled1 locationNCT05052216
Recruiting
Not Applicable

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

Atrial FibrillationObstructive Sleep Apnea
Tulane University60 enrolled3 locationsNCT04814420
Recruiting
Phase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

Obstructive Sleep Apnea
Amgen250 enrolled54 locationsNCT07226765
Recruiting
Phase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

ObesityObstructive Sleep Apnea
Amgen250 enrolled60 locationsNCT07225686
Recruiting
Not Applicable

Evaluating the Impact of Home-Based Sleep Apnea Diagnostic on Well-Being, Health Behavior, and AF Load in Patients With Atrial Fibrillation Using a Decentralized Platform

Sleep ApneaAtrial Fibrillation (AF)
Herlev and Gentofte Hospital936 enrolled1 locationNCT06618417
Recruiting
Phase 3

Non-invasive Ventilation or CPAP in OSA-COPD Following Admission for an Acute Hypercapnic Respiratory Failure

Chronic Obstructive Pulmonary Disease ExacerbationObstructive Sleep Apnea Exacerbation
Assistance Publique - Hôpitaux de Paris386 enrolled1 locationNCT07047092
Recruiting
Phase 3

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

ObesityOverweightSleep Apnea, Obstructive
Eli Lilly and Company800 enrolled129 locationsNCT07369011
Recruiting
Not Applicable

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

Quality of LifeElderlyCOPD+6 more
VA Office of Research and Development668 enrolled1 locationNCT04179981
Recruiting

Early Dental Risk Screening for Pediatric Sleep-Disordered Breathing

Sleep-disordered breathing (SDB)Obstructive Sleep Apnea (OSA)Early Risk Screening for Sleep Disordered Breathing in a Dental Setting
University of North Carolina, Chapel Hill60 enrolled1 locationNCT07581938
Recruiting
Phase 3

Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea

Obstructive Sleep ApneaSleep Apnea
Yale University250 enrolled1 locationNCT07332442
Recruiting
Phase 2

The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)

Chronic Obstructive Pulmonary DiseaseObstructive Sleep ApneaOverlap Syndrome
University of California, San Diego240 enrolled1 locationNCT05237505
Recruiting
Phase 2

Phototherapy for Non-responders to Oral Appliance Therapy for Obstructive Sleep Apnea

Obstructive Sleep Apnea
University of Alberta528 enrolled1 locationNCT06960200
Recruiting
Phase 2

Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk

Sleep DisturbanceSleep Apnea
University of Utah80 enrolled2 locationsNCT06649929
Recruiting
Not Applicable

OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?

Obstructive Sleep ApneaApnea, Obstructive Sleep
Connecticut Children's Medical Center130 enrolled1 locationNCT05911646
Recruiting
Not Applicable

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

Obstructive Sleep ApneaOSA COPD Overlap Syndrome
VA Office of Research and Development108 enrolled1 locationNCT02703207
Recruiting
Not Applicable

Obstructive Sleep Apnoea and Difficult Asthma (OSADA)

Asthma (Diagnosis)OSA - Obstructive Sleep ApneaCPAP Treatment
St. James's Hospital, Ireland80 enrolled1 locationNCT07160868
Recruiting

The Impact of Volume Overload on Obstructive Sleep Apnea in Patients With Congestive Heart Failure

Heart FailureObstructive Sleep Apnea (OSA)
Itshak Amsalem50 enrolled1 locationNCT07601724
Recruiting

Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension

HypertensionObstructive Sleep Apnea
Kaohsiung Armed Forces General Hospital100 enrolled1 locationNCT07603583