Sleep Apnea Clinical Trials

327 recruitingLast updated: July 11, 2026

There are 327 actively recruiting sleep apnea clinical trials across 48 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4, Phase 3, Early Phase 1. Top locations include Philadelphia, Pennsylvania, United States, Beijing, Beijing Municipality, China, Detroit, Michigan, United States. Updated daily from ClinicalTrials.gov.


Sleep Apnea Trials at a Glance

327 actively recruiting trials for sleep apnea are listed on ClinicalTrialsFinder across 6 cities in 48 countries. The largest study group is Not Applicable with 148 trials, with the heaviest enrollment activity in Philadelphia, Beijing, and Detroit. Lead sponsors running sleep apnea studies include VA Office of Research and Development, University Hospital, Antwerp, and Chinese University of Hong Kong.

Browse sleep apnea trials by phase

Treatments under study

About Sleep Apnea Clinical Trials

Looking for clinical trials for Sleep Apnea? There are currently 50 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sleep Apnea trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sleep Apnea clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 327 trials

Recruiting
Phase 1Phase 2

Atomoxetine and DAW2022 on OSA Severity

Obstructive Sleep Apnea
Brigham and Women's Hospital18 enrolled1 locationNCT05350215
Recruiting
Phase 3

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

ObesityOverweightSleep Apnea, Obstructive
Eli Lilly and Company800 enrolled129 locationsNCT07369011
Recruiting
Not Applicable

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

Obstructive Sleep ApneaDown Syndrome
Oregon Health and Science University304 enrolled7 locationsNCT05508971
Recruiting
Not Applicable

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils

Obstructive Sleep ApneaOtolaryngological Disease
Oregon Health and Science University175 enrolled2 locationsNCT06258837
Recruiting
Not Applicable

Myofunctional Therapy for Obstructive Sleep Apnea

Obstructive Sleep Apnea
University of Minnesota30 enrolled1 locationNCT07301125
Recruiting
Phase 4

Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury

Sleep ApneaSpinal Cord Injury
John D. Dingell VA Medical Center100 enrolled1 locationNCT02922894
Recruiting
Phase 2

Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea

Sleep Apnea, Obstructive
University of California, Los Angeles800 enrolled1 locationNCT00695214
Recruiting
Phase 2

Endotypic Traits and Obstructive Sleep Apnea Surgery

Obstructive Sleep Apnea
University of California, Los Angeles150 enrolled2 locationsNCT05953610
Recruiting
Phase 1Phase 2

Sleep Disordered Breathing With Opioid Use

Opioid UseSleep ApneaSleep-Disordered Breathing
VA Office of Research and Development150 enrolled1 locationNCT05589753
Recruiting
Not Applicable

Ansa Cervicalis and Hypoglossal Nerve Stimulation in OSA

Obstructive Sleep Apnea
Vanderbilt University Medical Center100 enrolled1 locationNCT05501236
Recruiting

Prospective Evaluation of New Metrics to Assess Cardiovascular Remodeling in Obstructive Sleep Apnea

Cardiovascular (CV) RiskObstructive Sleep Apnea
University Hospital, Antwerp270 enrolled1 locationNCT07427589
Recruiting

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

Pediatric Obstructive Sleep Apnea
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)120 enrolled1 locationNCT05052216
Recruiting
Phase 2

Acetazolamide in Central Sleep Apnea Patients Using Medication for Opioid Use Disorder

Central Sleep Apnea Comorbid With Opioid Use
Sanjay R Patel40 enrolled1 locationNCT06521476
Recruiting
Phase 2

Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea.

SnoringMild Obstructive Sleep Apnea
Johns Hopkins University100 enrolled1 locationNCT06587256
Recruiting

Bi-lateral HGN Therapy in Real-World Patients -Post Approval Research Investigation

Obstructive Sleep Apnea
Nyxoah Inc.229 enrolled2 locationsNCT07331285
Recruiting
Not Applicable

Innovative OSA Screening in Head and Neck Cancer Patients With the Apneal App

Head and Neck CancersObstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
University Hospital, Caen20 enrolled1 locationNCT06896448
Recruiting
Not Applicable

Treatment Failure of Continuous Positive Airway Pressure (CPAP) in Patients With Obstructive Sleep Apnea Syndrome (OSA): A Trial Comparing Polysomnography and the Sunrise Device to Drive Treatment-Adjustment Decisions.

Sleep Apnea Syndrome, Obstructive
University Hospital, Grenoble105 enrolled1 locationNCT07530302
Recruiting
Not Applicable

Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation

Sleep-disordered breathing (SDB)Obstructive Sleep ApneaArrhythmia+3 more
Beijing Anzhen Hospital658 enrolled27 locationsNCT07444372
Recruiting
Not Applicable

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

Atrial FibrillationObstructive Sleep Apnea
Tulane University60 enrolled3 locationsNCT04814420
Recruiting
Phase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

ObesityObstructive Sleep Apnea
Amgen250 enrolled60 locationsNCT07225686