Early PKD Observational Cohort Study
University of Kansas Medical Center
250 participants
Apr 1, 2016
OBSERVATIONAL
Conditions
Summary
This observational study will collect blood and urine and clinical information from individuals with early-stages of polycystic kidney disease (PKD), their unaffected siblings and normal volunteers to create a biobank, also called a biorepository. The long-term goal is to develop new knowledge on biological markers or biomarkers that indicate changes in the disease progression. An understanding of biomarkers for early renal cyst growth will benefit PKD patients as new therapies are being developed and tested.
Eligibility
Inclusion Criteria8
- Inclusion for early stage autosomal dominant polycystic kidney disease (ADPKD):
- Family history of PKD
- All races and ethnic groups
- Glomerular filtration rate (GFR) \>80 ml/min per 1.73 m2
- Inclusion for Healthy Volunteers:
- Male or female with no family history of kidney disease
- All races and ethnic groups
- Normal GFR
Exclusion Criteria4
- Non-insulin or insulin-dependent diabetes mellitus
- Systemic illness (i.e.systemic lupus erythematosus, vasculitis)
- Unable to provide written informed consent
- Unavailable for magnetic resonance imaging (MRI) and blood/urine collection
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Locations(3)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT02936791