Polycystic Kidney Disease Clinical Trials

6 recruiting

Frequently Asked Questions

Common questions about Polycystic Kidney Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 21 trials

Recruiting
Phase 3

Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)

Autosomal Dominant Polycystic Kidney Disease
The University of Queensland1,174 enrolled49 locationsNCT04939935
Recruiting
Phase 1

Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease

Autosomal Dominant Polycystic Kidney Disease
AstraZeneca40 enrolled15 locationsNCT07228364
Recruiting
Phase 2

A Study to Assess Adverse Events and Effectiveness of IntraVenous Infusions of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease
AbbVie240 enrolled75 locationsNCT06902558
Recruiting

Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease
Mayo Clinic40 enrolled1 locationNCT04344769
Recruiting

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

Cystic FibrosisHuntington DiseaseSickle Cell Disease+12 more
Assistance Publique - Hôpitaux de Paris550 enrolled1 locationNCT06147414
Recruiting

NOX4 and Related Biomarkers in ADPKD

Autosomal Dominant Polycystic Kidney Disease
Mayo Clinic60 enrolled1 locationNCT04630613
Recruiting

Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease

Autosomal Dominant Polycystic Kidney Disease (ADPKD
King's College London200 enrolled1 locationNCT07260071
Recruiting

Imaging Assessments of ARPKD Kidney Disease Progression

Autosomal Recessive Polycystic Kidney Disease
The Cleveland Clinic60 enrolled2 locationsNCT07201025
Recruiting

Polycystic Kidney Disease Data Repository

Polycystic Kidney Disease
The Rogosin Institute1,000 enrolled1 locationNCT00792155
Recruiting
Not Applicable

Well-Formulated Ketogenic Diet Polycystic Kidney Disease

Polycystic Kidney Disease
Ohio State University20 enrolled1 locationNCT06325644
Recruiting

PKD Clinical and Translational Core Study

Polycystic Kidney Disease
University of Maryland, Baltimore350 enrolled1 locationNCT01873235
Recruiting
Phase 2

Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease

Autosomal Dominant Polycystic Kidney Disease
Cantonal Hospital Graubuenden40 enrolled2 locationsNCT06435858
Recruiting
Phase 2

Trial of JMKX003142 in Participants With Rapidly Progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD)

ADPKD (Autosomal Dominant Polycystic Kidney Disease)
Jemincare135 enrolled1 locationNCT06800651
Recruiting

ARPKD Database Study

Autosomal Recessive Polycystic Kidney DiseaseHepato/Renal Fibrocystic DiseaseJoubert Syndrome
Children's Hospital of Philadelphia200 enrolled6 locationsNCT01401998
Recruiting

Early PKD Observational Cohort Study

Polycystic Kidney Disease
University of Kansas Medical Center250 enrolled3 locationsNCT02936791
Recruiting
Not Applicable

Effects of Exogenous Ketosis on Proteinuria and Renal Function

KetosisProteinuriaRenal Insufficiency, Chronic+1 more
Gødstrup Hospital43 enrolled1 locationNCT06867471
Recruiting
Not Applicable

Amnioinfusion for Fetal Renal Failure

Polycystic Kidney DiseaseMulticystic Dysplastic KidneyFetal Renal Anomaly+6 more
Fetal Care Center, PLLC35 enrolled1 locationNCT06728228
Recruiting

The German ADPKD Tolvaptan Treatment Registry

ADPKD (Autosomal Dominant Polycystic Kidney Disease)
University of Cologne2,000 enrolled12 locationsNCT02497521
Recruiting

Congenital Hepatic Fibrosis and Autosomal Recessive Polycystic Kidney Disease in Children at Sohag University Hospital

Congenital Hepatic Fibrosis and Autosomal Recessive Polycystic Kidney Disease in Children at Sohag University Hospital
Sohag University30 enrolled1 locationNCT06601829
Recruiting

ADPKD Patient Registry

Polycystic Kidney Diseases
PKD Foundation3,000 enrolled1 locationNCT04039061