RecruitingNot ApplicableNCT02948972
Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility
Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility: Complete Surgery + IVF Versus IVF (ENDOFERT)
Sponsor
University Hospital, Lille
Enrollment
120 participants
Start Date
Nov 17, 2016
Study Type
INTERVENTIONAL
Conditions
Summary
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)
Eligibility
Sex: FEMALEMin Age: 18 YearsMax Age: 38 Years
Inclusion Criteria6
- Primary and secondary infertility
- Indication for IVF
- Persistent pain related to endometriosis with analgesic medical treatment failure
- Persistent pain including at least one of the following digestive symptoms related to endometriosis: Dyschesia / Sub-occlusive syndrome / Rectal bleeding / Painful defecation
- Colorectal deep infiltrating endometriosis : Whatever lesion size / With at least rectal serosal involvement / Confirmed by MRI and 1 different investigation: vaginal ultrasound echography or coloscopic CT scan or rectal endoscope ultrasound
- Eligible for DIE surgery
Exclusion Criteria6
- Contraindication to pregnancy or to IVF
- Viral risk
- Previous IVF cycle(s)
- Previous colorectal surgery
- Need of myomectomy during surgery
- The use of oocytes donor
Interventions
PROCEDUREcomplete surgery
complete surgery of colorectal deep infiltrating endometriosis
PROCEDUREIn vitro fertilization without surgery
IVF without endometriosis surgery
Locations(5)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT02948972
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