RecruitingNot ApplicableNCT02948972

Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility

Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility: Complete Surgery + IVF Versus IVF (ENDOFERT)


Sponsor

University Hospital, Lille

Enrollment

120 participants

Start Date

Nov 17, 2016

Study Type

INTERVENTIONAL

Conditions

Summary

The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 38 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether surgery to remove a specific type of severe endometriosis (a condition where tissue similar to the lining of the uterus grows in the wrong places, including the bowel) can help women get pregnant. **You may be eligible if...** - You have not been able to get pregnant (either for the first time or again) - Your doctor has recommended IVF (in vitro fertilization) - You have ongoing pain related to endometriosis that pain medications haven't helped - Your endometriosis pain includes bowel symptoms like painful bowel movements, rectal bleeding, or near-blockages - Imaging tests (MRI plus at least one other scan) have confirmed endometriosis affecting your rectum or bowel - Your doctor thinks you are a good candidate for surgery **You may NOT be eligible if...** - There is a medical reason you cannot get pregnant or do IVF - You have certain viral infections that could affect treatment - You have done IVF before - You have had previous bowel surgery - You need a fibroid removal at the same time as the endometriosis surgery - You would need to use donor eggs Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREcomplete surgery

complete surgery of colorectal deep infiltrating endometriosis

PROCEDUREIn vitro fertilization without surgery

IVF without endometriosis surgery


Locations(5)

CHU

Clermont-Ferrand, France

Hôpital Jeanne de Flandres, CHRU

Lille, France

AP-HP, Hôpital Tenon

Paris, France

CHU

Poissy, France

CHU

Rouen, France

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NCT02948972


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