RecruitingNCT02967068

VCRC Tissue Repository

VCRC Tissue Biorepository Collection Protocol

Sponsor

University of Pennsylvania

Enrollment

1,000 participants

Start Date

Nov 1, 2016

Study Type

OBSERVATIONAL

Conditions

Microscopic Polyangiitis Giant Cell Arteritis Takayasu Arteritis IgA Vasculitis Eosinophilic Granulomatosis With Polyangiitis Churg-Strauss Syndrome Henoch-Schonlein Purpura Granulomatosis With Polyangiitis (Wegener's)Polyarteritis Nodosa Aortitis Cutaneous Vasculitis

Summary

The purpose of this study is to collect existing tissue specimens from subjects enrolled in Vasculitis Clinical Research Consortium (VCRC) studies. Analysis of these tissue specimens and linked clinical data collected through VCRC studies may lead to the identification and development of a series of translational research projects. Results of these studies will provide vasculitis researchers with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.

Eligibility

Plain Language Summary

Simplified for easier understanding

This tissue repository collects biological samples (such as blood or tissue) from patients who are enrolled in related Vasculitis Clinical Research Consortium (VCRC) studies. Researchers use these samples to study rare inflammatory blood vessel diseases and develop better diagnostics and treatments. You may be eligible if: - You are currently or were previously enrolled in one of the VCRC observational or interventional studies (specific protocol numbers: 5502–5507, 5522–5527, 5562, 5563) You may NOT be eligible if: - You are unable to give informed consent (and do not have a guardian to do so) - You do not wish for your tissue samples to be used for research purposes Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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