RecruitingPhase 2NCT02989025

Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia

Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia-The PROGRESS Pilot Study


Sponsor

University of Mississippi Medical Center

Enrollment

60 participants

Start Date

May 22, 2017

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to learn if giving 17-hydroxyprogesterone caproate (17 OHPC) to mothers with preeclampsia diagnosed before 34 weeks gestation improves mother and baby outcomes.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether progesterone (a hormone) can help safely extend pregnancy and improve outcomes in women who develop a serious pregnancy complication called severe preeclampsia (dangerously high blood pressure during pregnancy) before 34 weeks of pregnancy. **You may be eligible if...** - You are between 23 and 34 weeks pregnant - You have been diagnosed with severe or superimposed preeclampsia (high blood pressure with other complications in pregnancy) - You are a patient at UMMC (University of Mississippi Medical Center) - You are willing and able to understand and agree to participate **You may NOT be eligible if...** - You are more than 33 weeks or fewer than 23 weeks pregnant - You or your baby need emergency delivery right away (due to serious complications like placental abruption, blood clotting problems, fluid in the lungs, or the baby's heart rate showing dangerous signs) - You have other conditions that make extending the pregnancy unsafe Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG17 OHPC

The study participant will be given 17 OHPC, 250mg IM at admission and every 7 days thereafter.


Locations(1)

Winfred L. Wiser Hospital

Jackson, Mississippi, United States

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NCT02989025


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