RecruitingNot ApplicableNCT02993900

Image-Guided Gynecologic Brachytherapy

A Clinical Trial To Evaluate Image-Guided Gynecologic Brachytherapy In The MR Simulator Suite

Sponsor

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Enrollment

54 participants

Start Date

Dec 15, 2016

Study Type

INTERVENTIONAL

Conditions

Cervical Cancer Bladder Cancer Uterine Cancer Vaginal Cancer Vulvar Cancer

Summary

This research is being done to evaluate multimodality imaging, including magnetic resonance imaging-guided therapy (MRT), as a possible treatment for gynecologic cancers. The therapy takes place in the Department of Radiation Oncology at the Johns Hopkins SKCCC. The purpose of this study is to investigate the ability of MRI to successfully guide the placement of the brachytherapy applicator necessary to treat participants' gynecologic cancer. The Investigators want to see if the use of MRI will do a better job of assessing the tumor at the time of brachytherapy than the routinely used CT scan. The Investigators also want to determine if the use of MRI will enable doctors to reduce the radiation dose received by the body during the process of treating the tumor.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study is using image-guided brachytherapy — a type of internal radiation treatment guided by MRI or CT scans — to precisely treat gynaecological cancers (such as cervical, uterine, or vaginal cancer), and to track how well this approach works over time. **You may be eligible if...** - You have been diagnosed with a gynaecological cancer confirmed by a tissue sample - You have cervical cancer (any stage from I to IVA, or a vaginal recurrence) - You have uterine cancer at stage IIIB (with vaginal involvement) or a vaginal recurrence - You are eligible for internal radiation treatment (brachytherapy) **You may NOT be eligible if...** - You have cancer that has spread far beyond the pelvis (distant metastases) - You are not eligible for internal radiation based on your cancer stage or location - You have health conditions that would make radiation therapy unsafe Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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