Patient-Centered NeuroRehabilitation (PCN)
Patient-Centered NeuroRehabilitation
University of Michigan
500 participants
Jun 1, 2016
INTERVENTIONAL
Conditions
Summary
As individuals grow older, a number of factors can reduce our cognitive (or thinking) abilities such as "normal" aging, neurodegenerative diseases, and cardiovascular disease. This study will evaluate whether cognitive rehabilitation and transcranial electrical stimulation (TES) can improve cognitive abilities. Cognitive rehabilitation refers to methods that are used to improve tasks people have trouble doing in everyday life. Transcranial electrical stimulation uses small amounts of electricity to try to alter brain functioning. These approaches may help improve cognitive abilities like attention, learning, memory, finding words, and problem solving as well as everyday functioning. The goal of this study is to identify how to best use these methods, either alone or in combination.
Eligibility
Inclusion Criteria2
- Individuals who have reported cognitive dysfunction and cognitively intact participants.
- Participants will be age 50 or older
Exclusion Criteria5
- A history of epilepsy
- Sensory or motor impairments that limit the ability to take part in the study
- Current alcohol or drug abuse/dependence
- Those who are currently pregnant or may become pregnant during the duration of the study (if there is a question of pregnancy, pregnancy tests will be available for participants at no charge)
- Those who are being evaluated for TES methodology will also be excluded for 1) metallic or electronic implant 2) skull plates or other cranial implants that affect TES
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Interventions
Participants will receive active tDCS at up to 4mA per electrode for up to 40 minutes for up to 260 sessions.
Participants will receive sham tDCS for up to 260 sessions
Participants may receive a cognitively based intervention that targets the particular cognitive and/or functional abilities of interest. This includes methods of cognitive training, cognitive remediation, and cognitive rehabilitation for up to 260 sessions
Participants will receive active transcranial alternating current stimulation at up to 4mA per electrode for up to 40 minutes for up to 260 sessions
Participants will receive sham transcranial alternating current stimulation for up to 260 sessions
Participants will receive active transcranial random noise stimulation at up to 4mA per electrode for up to 40 minutes for up to 260 sessions
Participants will receive sham transcranial random noise stimulation for up to 260 sessions
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03036319