RecruitingNot ApplicableNCT06820125

Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation

Isolated Versus Combined Cognitive and Motor High-tech Rehabilitation in Patients with Multiple Sclerosis


Sponsor

Universita di Verona

Enrollment

48 participants

Start Date

Jul 5, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The first aim of this project is to investigate the effects of different high-tech neurorehabilitation interventions (cognitive, motor, and combined cognitive-motor) on both cognitive and motor disability outcomes in people with multiple sclerosis (MS). The second aim is to identify the cognitive and motor profiles of MS patients who benefit the most from either the combined cognitive-motor rehabilitation intervention or the isolated cognitive or motor treatments.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares two types of high-technology rehabilitation for people with multiple sclerosis (MS) who have both thinking and walking difficulties: one that trains only cognitive (thinking) skills, and one that combines cognitive and motor (movement) training using specialized equipment. **You may be eligible if...** - You have multiple sclerosis with mild to severe cognitive impairment (confirmed by neuropsychological testing) - You have mild to moderate walking disability - You have not had a relapse or been on steroids for the past 3 months - You have adequate vision and hearing to use computer software **You may NOT be eligible if...** - You have a neurological condition other than MS - You have a major psychiatric disorder - You have high levels of anxiety or depression (above specified thresholds) - You have other conditions that would interfere with using the rehabilitation technology Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICECognitive rehabilitation: CG group

60 minutes of cognitive training with a computerized device

DEVICEMotor rehabilitation: MG group

60 minutes of robot-assisted gait training with the G-EO System

DEVICECombined rehabilitation: CbG group

30 minutes of cognitive training with a computerized device + 30 minutes of robot-assisted gait training with the G-EO System. To mitigate the effects of fatigue in sequential training, the patients included in this group will undergo the cognitive (treatment CG) and motor (treatment MG) sessions in a counterbalanced order (half of the participants will follow the CG-MG sequence, and the other half will follow the MG-CG sequence). Five-minute breaks will be provided between the cognitive and motor sessions.


Locations(1)

Sezione medicina fisica e riabilitativa dipartimento di neuroscienze

Verona, verona, Italy

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NCT06820125


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