Microbiota and the Lung Cancer

This study investigates the relationship between the bacteria and microbes living in the gut and lungs (the microbiome) and lung cancer, by collecting samples before and after surgery, to understand whether the microbiome plays a role in cancer development or treatment response. **You may be eligible if...** - You have been diagnosed with non-small cell lung cancer and are scheduled for surgery (with or without pre-surgery chemotherapy) - Your BMI is under 29.9 kg/m² - You have not taken antibiotics, steroids, or immune-suppressing medications in the 2 months before joining the study - You have not taken prebiotic or probiotic supplements in the 2 months before joining - You are enrolled in or covered by a national health insurance system **You may NOT be eligible if...** - You have cognitive difficulties that prevent understanding and consenting - You had a serious digestive or lung infection requiring antibiotics in the 2 months before the study - You have an inflammatory bowel disease (such as Crohn's disease or colitis) - You have had previous esophageal surgery, colostomy, or partial/total stomach removal - You are participating in another clinical trial with experimental treatments Talk to your doctor to see if this trial is right for you.