RecruitingNot ApplicableNCT03071536

Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation

Furosemide Stress Test as a Marker of Postoperative Kidney Allograft Function


Sponsor

King Chulalongkorn Memorial Hospital

Enrollment

180 participants

Start Date

Nov 25, 2016

Study Type

INTERVENTIONAL

Summary

Furosemide is an old drug that has been used frequently in the postoperative period of kidney transplantation, aiming to achieve adequate urine output. There is no previous study that directly evaluate the urine response to standardized dose of furosemide in the postoperative period. The objective is to measure the urine output after standardized dose of furosemide is delivered, as a biomarker to predict the graft function in perioperative period.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria2

  • Deceased donor kidney transplantation at KCMH
  • informed consent is accepted

Exclusion Criteria3

  • Known allergy to furosemide
  • Surgical complication of allograft
  • Urgently needed for dialysis (refractory hypervolemia, uremic symptoms, and hyperkalemia)

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Interventions

DRUGFurosemide Injection

Furosemide 1.5 mg/kg intravenously at 3 hours post-reperfusion of kidney allograft


Locations(1)

King Chulalongkorn Memorial Hospital

Bangkok, Thailand

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NCT03071536