Modulation of Anti-tumor T Cell Responses in Cancer Patients Treated by Concomitant Radiochemotherapy

This study is looking at how the immune system — specifically the cells that fight cancer — responds when lung cancer or head and neck cancer patients receive radiation and chemotherapy at the same time. **You may be eligible if...** - You have been diagnosed with non-small cell lung cancer, small cell lung cancer, or head and neck cancer (confirmed by a tissue biopsy) - You are scheduled to receive radiation and chemotherapy together as your first treatment - You are willing to sign a consent form **You may NOT be eligible if...** - You are scheduled for radiation alone, stereotactic radiation, or radiation given before and after chemotherapy (not at the same time) - You have already received radiation and chemotherapy together for a previous cancer - You are currently taking immunotherapy, chemotherapy, or other immune-suppressing medications Talk to your doctor to see if this trial is right for you.