Red Light Treatment in Peripheral Artery Disease
Vasodilatory Effects of Light on Peripheral Artery Disease
University of Alabama at Birmingham
40 participants
Jan 17, 2018
INTERVENTIONAL
Conditions
Summary
Subjects with a known diagnosis of peripheral artery disease as measured by an abnormal ankle brachial index (\<.9 or \>1.1) will undergo a single 5 min exposure of 670 nm light, 1 cm above the gastrocnemius muscle. Blood flow will be measured by infusion of ultrasound contrast and subsequent acquisition of ultrasound images. 2 blood samples will be collected for measurement of nitric oxide metabolites.
Eligibility
Plain Language Summary
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Interventions
Light Emitting Diode light source (670 nm wavelength with output up to 75mW/cm2) will be placed over the gastrocnemius muscle. The light will be on for 5 minutes.
All subjects will undergo infusion of octafluoropropane to measure peripheral blood flow.
Locations(1)
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NCT03203239