Red Light Treatment in Peripheral Artery Disease

This study tests whether red light therapy — using near-infrared light to stimulate blood vessel function — can improve blood flow and walking ability in patients with peripheral artery disease (PAD). PAD occurs when narrowed arteries reduce blood flow to the legs, causing cramping and pain during activity. This non-invasive approach may offer relief without surgery. You may be eligible if: - You are between 18 and 85 years old - You have been diagnosed with peripheral artery disease (PAD), confirmed by an ankle-brachial index below 0.9 or above 1.1 - You can understand the consent process - You can read and speak English You may NOT be eligible if: - You are pregnant - You have a known allergy to ultrasound contrast agents (perflutren) - You have pulmonary hypertension - You are using illicit drugs - You have uncontrolled high blood pressure (over 160/95) - You have sickle cell disease or a history of a heart hole (intracardiac shunt) - You have spinal stenosis, unspecified pain disorders, or uncontrolled medical conditions Talk to your doctor to see if this trial is right for you.